コンテンツへスキップ
Merck

DRD4

dopamine receptor D4

別名:
D4DR
Species:
Human DRD4 (1815), Mouse Drd4 (13491), Rat Drd4 (25432), domestic guinea pig Drd4 (100733356), naked mole-rat Drd4 (101708437), chicken DRD4 (423016), dog DRD4 (607223), dog DRD4 (448805)
UniProtKB ID:
P21917, B0M0J7, Q7Z7Q5, Q8NGM5
遺伝子ID:
  • Human(1815) Summary: This gene encodes the D4 subtype of the dopamine receptor. The D4 subtype is a G-protein coupled receptor which inhibits adenylyl cyclase. It is a target for drugs which treat schizophrenia and Parkinson disease. Mutations in this gene have been associated with various behavioral phenotypes, including autonomic nervous system dysfunction, attention deficit/hyperactivity disorder, and the personality trait of novelty seeking. This gene contains a polymorphic number (2-10 copies) of tandem 48 nt repeats; the sequence shown contains four repeats. [provided by RefSeq, Jul 2008]
  • Mouse(13491) dopamine receptor D4
  • Rat(25432) dopamine receptor D4
  • domestic guinea pig(100733356) dopamine receptor D4
  • naked mole-rat(101708437) dopamine receptor D4
  • chicken(423016) dopamine receptor D4
  • dog(607223) dopamine receptor D4
  • dog(448805) dopamine receptor D4

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Small Molecule - Agonist

製品番号
詳細
Species
P233
PD 168,077 マレイン酸塩, powder,
Species
human
1041008
R-(−)-アポモルフィン 塩酸塩 ヘミ水和物, United States Pharmacopeia (USP) Reference Standard,
Species
human
R2530
ロピニロール 塩酸塩, powder, ≥98% (HPLC),
Species
human
A1237
プラミペキソール 二塩酸塩, >98% (HPLC), powder,
Species
human
1605205
ロピニロール 塩酸塩, United States Pharmacopeia (USP) Reference Standard,
Species
human

Small Molecule - Antagonist

製品番号
詳細
Species
L131
L-745,870 塩酸塩, ,
Species
human
U115
U-101958 マレイン酸塩, solid,
Species
human
L135
L-741,626, ≥98% (HPLC),
Species
human
C-904
クロルプロマジン 塩酸塩, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®,
Species
human
1229001
ドロペリドール, United States Pharmacopeia (USP) Reference Standard,
Species
human

Antibodies

製品番号
詳細
交差性
アプリケーション
MABN125
抗DRD4抗体 クローン2B9, clone 2B9, from mouse,
交差性
human, mouse, rat
アプリケーション
immunocytochemistry
western blot
AB1787P
Anti-Dopamine D4 Receptor Antibody, extracellular domain, Chemicon®, from rabbit,
交差性
mouse
アプリケーション
ELISA
western blot
HPA062682
Anti-Drd4 Antibody Produced In Rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunofluorescence
324405
Anti-Dopamine D₄ Receptor Rabbit pAb, lyophilized, Calbiochem®,
交差性
human, rat
アプリケーション

Small Molecule - Inhibitor

製品番号
詳細
Species
D052
GBR 12909 二塩酸塩, solid, ≥98% (HPLC),
Species
human
B102
ブプロピオン 塩酸塩, ≥98% (HPLC), solid,
Species
human
1031401
アモキサピン, United States Pharmacopeia (USP) Reference Standard,
Species
human
A-123
アモキサピン, 1.0 mg/mL in methanol, certified reference material, Cerilliant®,
Species
human
PHR1841
アモキサピン, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human

Small Molecule - Metabolite

製品番号
詳細
Species
H3132
3-Hydroxy-4-methoxyphenethylamine hydrochloride, ,
Species
human
M4251
3-メトキシチラミン 塩酸塩, ≥95.5%, crystalline,
Species
human

Small Molecule - Mixed Agonist/Antagonist

製品番号
詳細
Species
B9308
BP897, >98% (HPLC), solid,
Species
human, rat
H1512
ハロペリドール, powder,
Species
human, rat
C6305
クロザピン, ,
Species
human, rat

Small Molecule - Precursor

製品番号
詳細
Species
D9628
3,4-ジヒドロキシ-L-フェニルアラニン, ≥98% (TLC),
Species
mouse, human, rat
D9503
3,4-ジヒドロキシ-DL-フェニルアラニン, ,
Species
mouse, human, rat

esiRNA

製品番号
詳細
Species
EMU028911
MISSION® esiRNA, targeting mouse Drd4,
Species
mouse