Chemical biology products incorporate the techniques and strengths of chemistry to address fundamentally important questions in biology, medicine, and drug discovery. Sigma-Aldrich® chemical biology products provide solutions, expertise, and industry leadership to advance your research. We offer a market-leading range of innovative products for conjugation strategies, such as azide-alkyne cycloaddition chemistry, as well as synthetic intermediates and building blocks for the synthesis of biomolecules, such as peptides, carbohydrates, and oligonucleotides.
Our protein degrader building blocks are the easiest way to generate libraries of protein degraders, such as proteolysis targeting chimeras (PROTAC® molecules), that can be screened for effective degradation of your target protein from cells.
Our portfolio of click chemistry reagents includes a variety of azides, alkynes, catalysts, and ligands to accelerate your progress in chemical biology, polymer chemistry, bioconjugation, and drug discovery.
Our portfolio of linkers and crosslinkers provide structural stability and reliability in protein-protein, protein-peptide, and peptide/protein-small molecule interactions for all your bioconjugation needs.