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Safety Information

1559709

USP

Prekallikrein Activator

United States Pharmacopeia (USP) Reference Standard

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About This Item

UNSPSC Code:
41116107
NACRES:
NA.24

grade

pharmaceutical primary standard

manufacturer/tradename

USP

application(s)

pharmaceutical

format

neat

storage temp.

−20°C

General description

Prekallikrein activator (PKA), also known as Factor XIIa, activates prekallikrein to kallikrein. Activated kallikrein cleaves kininogens into kinins (e.g., bradykinin) that can result in a loss of blood pressure. PKA is assayed by its ability to activate prekallikrein, which once activated cleaves a synthetic peptide substrate and releases a chromophore that can be measured spectrophotometrically. The amount of PKA is determined by comparison with reference standard material. Prekallikrein Activator USP Reference standard is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia

Application

Prekallikrein Activator USP Reference standard, is used to prepare standard solutions for prekallikrein activator assay. Further information is available in chapter, 〈165〉 PREKALLIKREIN ACTIVATO, USP43-NF38 – 6583 of United States Pharmacopeia (USP).

Other Notes

This product is part of the USP Biologics program.
Sales restrictions may apply.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

1559709:
1559709-22.5IU:


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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