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Key Documents

Safety Information

1111103

USP

Chlorhexidine acetate

United States Pharmacopeia (USP) Reference Standard

Synonym(s):

Chlorhexidine diacetate salt

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About This Item

Empirical Formula (Hill Notation):
C22H30Cl2N10 · 2C2H4O2
CAS Number:
56-95-1
Molecular Weight:
625.55
UNSPSC Code:
41116107
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

chlorhexidine

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

InChI

1S/C22H30Cl2N10.2C2H4O2/c23-15-5-9-17(10-6-15)31-21(27)33-19(25)29-13-3-1-2-4-14-30-20(26)34-22(28)32-18-11-7-16(24)8-12-18;2*1-2(3)4/h5-12H,1-4,13-14H2,(H5,25,27,29,31,33)(H5,26,28,30,32,34);2*1H3,(H,3,4)

InChI key

WDRFFJWBUDTUCA-UHFFFAOYSA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Chlorhexidine acetate USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Chlorhexidine Acetate Topical Solution
  • Chlorhexidine Gluconate Oral Rinse
  • Chlorhexidine Gluconate Solution
  • Chlorhexidine Gluconate Topical Gel
  • Chlorhexidine Gluconate Topical Solution
  • Chlorhexidine Hydrochloride

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

related product

Product No.
Description
Pricing

C1510000

Chlorhexidine, European Pharmacopoeia (EP) Reference Standard

C1520000

Chlorhexidine diacetate, European Pharmacopoeia (EP) Reference Standard

C1540000

Chlorhexidine dihydrochloride, European Pharmacopoeia (EP) Reference Standard

PHR1294

Chlorhexidine digluconate, Pharmaceutical Secondary Standard; Certified Reference Material

Y0001545

Chlorhexidine for system suitability, European Pharmacopoeia (EP) Reference Standard

PHR1421

Chlorhexidine, Pharmaceutical Secondary Standard; Certified Reference Material

PHR1459

Chlorhexidine Hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material

1111001

Chlorhexidine, United States Pharmacopeia (USP) Reference Standard

1111012

Chlorhexidine System Suitability Mixture, United States Pharmacopeia (USP) Reference Standard

BP068

Chlorhexidine acetate, British Pharmacopoeia (BP) Reference Standard

Signal Word

Warning

Hazard Statements

H302,H315,H319,H371,H410

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 2

Target Organs

Liver,Teeth

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

1111103-200MG:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Wen-Shuai Liu et al.
Chemical biology & drug design, 85(1), 91-97 (2014-09-13)
Five N-methyl-N-R-N,N-bis(2-hydroxyethyl) ammonium bromides (R = -benzyl (chloride, BNQAS), -dodecyl (C12QAS), -tetradecyl (C14QAS), -hexadecyl (C16QAS), -octadecyl (C18QAS)) were prepared based on N-methyldiethanolamine (MDEA) and halohydrocarbon. Five QAS were characterized by FTIR, NMR, and MS. BNQAS, C12QAS, C14QAS, and C16QAS were
Manikandan Ekambaram et al.
Journal of dentistry, 42(6), 709-719 (2014-04-16)
To examine the effect of adjunctive application of chlorhexidine (CHX) and ethanol-wet bonding (EWB) on bond durability and nanoleakage of hydrophobic adhesive to sound (SD) and caries-affected dentine (CAD). Dentine surfaces of molars were etched after caries removal and randomly
Manikandan Ekambaram et al.
Journal of dentistry, 42(7), 872-882 (2014-02-25)
To evaluate the effect of adjunctive application of ethanol-wet bonding and chlorhexidine (CHX) with a hydrophobic adhesive on bond durability of fibre posts to intraradicular dentine. Ninety-six extracted human teeth with a single root and root canal were prepared for
M G Bueno et al.
Oral diseases, 21(1), 57-65 (2013-11-14)
The antimicrobial action of five drugs incorporated in temporary denture relines on the fungal biofilm was evaluated. A Candida albicans biofilm (SC5314) was formed on specimens (10 × 1 mm) of materials (Trusoft and Softone) modified or not (control) by
R C Beier et al.
Journal of applied microbiology, 118(2), 326-342 (2014-11-29)
To evaluate susceptibility of Pseudomonas aeruginosa veterinary isolates to antibiotics and disinfectants. Pseudomonas aeruginosa isolates collected from dogs (n = 155) and other animals (n = 20) from sixteen states during 1994-2003 were tested for susceptibility. Most isolates were resistant

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