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Safety Information

PHL83525

Morusin

phyproof® Reference Substance

Synonym(s):

2-(2,4-Dihydroxyphenyl)-5-hydroxy-8,8-dimethyl-3-(3-methyl-2-buten-1-yl)-4H,8H-benzo[1,2-b:3,4-b′]dipyran-4-one, Mulberrochromene

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About This Item

Empirical Formula (Hill Notation):
C25H24O6
CAS Number:
Molecular Weight:
420.45
MDL number:
UNSPSC Code:
41116107
NACRES:
NA.24

grade

primary reference standard

product line

phyproof® Reference Substance

Assay

≥90.0% (HPLC)

manufacturer/tradename

PhytoLab

application(s)

food and beverages

format

neat

storage temp.

2-8°C

InChI

1S/C25H24O6/c1-13(2)5-7-17-22(29)21-19(28)12-20-16(9-10-25(3,4)31-20)24(21)30-23(17)15-8-6-14(26)11-18(15)27/h5-6,8-12,26-28H,7H2,1-4H3

InChI key

XFFOMNJIDRDDLQ-UHFFFAOYSA-N

General description

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

Application


  • Anti-fatigue properties: Morusin is studied for its role in combating fatigue. The research explores its bioguided isolation and bioactivity, suggesting potential applications in health supplements for enhanced physical performance and resilience (Chen et al., 2024).

  • Anti-cancer activity in breast cancer: Morusin has been found to inhibit breast cancer-induced osteolysis by targeting the PI3K-mTOR signaling pathway, showcasing its therapeutic potential in cancer treatment (Zhang et al., 2024).

  • Aortic valve calcification: Research demonstrates Morusin′s ability to alleviate aortic valve calcification by inhibiting senescence in valve interstitial cells through the Ccnd1/Trim25/Nrf2 axis, highlighting its potential in cardiovascular disease management (Liu et al., 2024).

  • Suppression of gastric cancer cell stemness: Morusin is effective in suppressing the stemness characteristics of gastric cancer cells under hypoxic conditions by inhibiting HIF-1α accumulation, providing insights into its use in limiting cancer progression (Chen et al., 2024).

  • Chemo-photothermal therapy: A Morusin-Cu(II)-indocyanine green nanoassembly has been developed for cancer therapy, igniting mitochondrial dysfunction and enhancing the therapeutic outcomes of chemo-photothermal treatment strategies (Ran et al., 2024).


Legal Information

phyproof is a registered trademark of PhytoLab GmbH & Co. KG

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

PHL83525-10MG:


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