PHL83283

Scutellarein

phyproof^® Reference Substance

• Synonym(s): 4′,5,6,7-Tetrahydroxyflavone, 6-Hydroxyapigenin
• Empirical Formula (Hill Notation): C₁₅H₁₀O₆
• CAS Number: 529-53-3
• Molecular Weight: 286.24
• MDL number: MFCD00017692
• UNSPSC Code: 41116107
• NACRES: NA.24

Properties

• grade: primary reference standard
• product line: phyproof^® Reference Substance
• Assay: ≥95.0% (HPLC)
• manufacturer/tradename: PhytoLab
• application(s): food and beverages
• format: neat
• SMILES string: Oc1ccc(cc1)C2=CC(=O)c3c(O)c(O)c(O)cc3O2
• InChI: 1S/C15H10O6/c16-8-3-1-7(2-4-8)11-5-9(17)13-12(21-11)6-10(18)14(19)15(13)20/h1-6,16,18-20H
• InChI key: JVXZRQGOGOXCEC-UHFFFAOYSA-N

Description

General description

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

Biochem/physiol Actions

Flavonoid that is selectively cytotoxic toward cancer cells. Induces mitochondrial ROS, DNA damage, and metabolic suppression, preferentially in tumor cells. Scutellarein has been shown to have better absorption than scutellarin in Caco-2 monolayer cells.

Other Notes

This compound is commonly found in plants of the genus: plantago

Legal Information

phyproof is a registered trademark of PhytoLab GmbH & Co. KG

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable