20124AST
Astec® CYCLOBOND™ I 2000 AC Chiral HPLC Column
5 μm particle size, L × I.D. 25 cm × 4.6 mm
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About This Item
Recommended Products
material
stainless steel column
Quality Level
product line
Astec®
packaging
pkg of 1 ea
manufacturer/tradename
Astec®
parameter
0-50 °C temperature
172 bar pressure (2500 psi)
technique(s)
HPLC: suitable
LC/MS: suitable
L × I.D.
25 cm × 4.6 mm
matrix
silica particle platform
matrix active group
cyclodextrin, beta- phase
particle size
5 μm
pore size
100 Å
operating pH
3.5-7
separation technique
chiral
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General description
CYCLOBOND I 2000 AC is used primarily for aromatic alcohols or amines that are chiral on the α or β carbon.
Resources:
CYCLOBOND FAQs
CYCLOBOND Reference Bibliography
Chiral Product Literature
- Bonded phase: Acetylated beta-cyclodextrin
Resources:
CYCLOBOND FAQs
CYCLOBOND Reference Bibliography
Chiral Product Literature
Legal Information
Astec is a registered trademark of Merck KGaA, Darmstadt, Germany
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Separation of Beraprost sodium isomers using different cyclodextrin stationary phases
Journal of Chromatography A, 633 (1-2), 97-103 (1993)
Optical resolution of flavanones by high-performance liquid chromatography on various chiral stationary phases
Journal of Chromatography A, 514, 147-159 (1990)
Journal of chromatography. A, 1305, 94-101 (2013-08-03)
Isochromene derivatives are very important precursors in the natural products industry. Hence the enantiomeric separations of chiral isochromenes are important in the pharmaceutical industry and for organic asymmetric synthesis. Here we report enantiomeric separations of 21 different chiral isochromene derivatives
Archives of pharmacal research, 23(3), 230-236 (2000-07-15)
(1'R, 2R)-, (1'R, 2S)-, (1'S, 2R)- and (1'S, 2S)-alpha-hydroxymetoprolol; (2R)- and (2S)-O-desmethylmetoprolol; and (2R)- and (2S)-metoprolol acid are major metabolites of (2R)-and (2S)-metoprolol, beta-adrenergic antagonist. The focus of most chiral separation methods until now has been on determination of the
Reprint of: Enantiomeric separation of functionalized ethano-bridged Troger bases using macrocyclic cyclofructan and cyclodextrin chiral selectors in high-performance liquid chromatography and capillary electrophoresis with application of principal component analysis
Journal of Chromatography. B, Biomedical Applications, 968, 40-48 (2014)
Related Content
CYCLOBOND is the name given to Astec technology for bonding cyclodextrins to a high purity silica gel through a stable ether linkage.
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