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Safety Information

T9573

Sigma-Aldrich

Anti-phospho-Tyrosine Hydroxylase (pSer40) antibody produced in rabbit

affinity isolated antibody, aqueous glycerol solution, sufficient for 10 blots

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About This Item

MDL number:
MFCD03792023
UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

Quality Level

200

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

aqueous glycerol solution

usage

sufficient for 10 blots

mol wt

antigen 60 kDa

species reactivity

rat, mouse, human

technique(s)

immunohistochemistry: 1:1000
western blot: 1:1000 using lysates of PC-12 Cells stimulated by Okadaic Acid (1 μM for 60 minutes)

UniProt accession no.

P07101

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

phosphorylation (pSer40)

Gene Information

human ... TH(7054)
mouse ... Th(21823)
rat ... Th(25085)

Specificity

Specifically recognizes tyrosine hydroxylase phosphorylated at serine 40.

Immunogen

synthetic phosphorylated peptide corresponding to amino acids residues surrounding the rat TH phosphorylated on serine 40.

Physical form

Solution in 10 mM HEPES, pH 7.5, 150 mM NaCl, 100 μg/ml BSA and 50% glycerol

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319

Precautionary Statements

P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

T9573-1VL:
T9573-100UL-PW:
T9573-100UL:
T9573-VAR:
T9573-BULK:

Certificates of Analysis (COA)

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Yusu Gu et al.
Endocrinology, 151(10), 4820-4829 (2010-07-30)
Exaggerated adrenergic activity is associated with human hypertension. The peptide urocortin 2 (Ucn 2) inhibits catecholamine synthesis and secretion from adrenal chromaffin cells in vitro and administration to mammals lowers blood pressure (BP). The chromogranin A-null mouse (Chga-/-) manifests systemic
Erica G Landis et al.
Investigative ophthalmology & visual science, 62(1), 28-28 (2021-01-28)
Exposure to high-intensity or outdoor lighting has been shown to decrease the severity of myopia in both human epidemiological studies and animal models. Currently, it is not fully understood how light interacts with visual signaling to impact myopia. Previous work
Alán Alpár et al.
The EMBO journal, 37(21) (2018-09-14)
Stress-induced cortical alertness is maintained by a heightened excitability of noradrenergic neurons innervating, notably, the prefrontal cortex. However, neither the signaling axis linking hypothalamic activation to delayed and lasting noradrenergic excitability nor the molecular cascade gating noradrenaline synthesis is defined.
Scot McIntosh et al.
Frontiers in psychiatry, 4, 88-88 (2013-08-24)
Chronic cocaine administration regulates the expression of several proteins related to dopaminergic signaling and synaptic function in the mesocorticolimbic pathway, including the prefrontal cortex. Functional abnormalities in the prefrontal cortex are hypothesized to be due in part to the expression
András H Lékó et al.
Scientific reports, 7(1), 3396-3396 (2017-06-15)
Adaptation to motherhood includes maternal behaviour and lactation during the postpartum period. The major organizing centres of maternal behaviour and lactation are located in the hypothalamic medial preoptic area (MPOA) and the arcuate nucleus, respectively. Insulin-like growth factor I (IGF-I)

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