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T8948

Sigma-Aldrich

1-(α,α,α-Trifluoro-m-tolyl)piperazine hydrochloride

99%

Synonym(s):

N-[3-(Trifluoromethyl)phenyl]piperazine hydrochloride, TFMPP hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C11H13F3N2 · HCl
CAS Number:
16015-69-3
Molecular Weight:
266.69
EC Number:
240-153-2
MDL number:
MFCD00039033
UNSPSC Code:
12352200
PubChem Substance ID:
24900576
NACRES:
NA.77

Assay

99%

drug control

regulated under CDSA - not available from Sigma-Aldrich Canada

availability

not available in Japan

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

mp

239-241 °C (lit.)

solubility

methanol:glacial acetic acid (1:1): soluble 25 mg/mL

application(s)

forensics and toxicology
veterinary

SMILES string

Cl.FC(F)(F)c1cccc(c1)N2CCNCC2

InChI

1S/C11H13F3N2.ClH/c12-11(13,14)9-2-1-3-10(8-9)16-6-4-15-5-7-16;/h1-3,8,15H,4-7H2;1H

InChI key

DGNLGWJZZZOYPT-UHFFFAOYSA-N

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Preparation Note

1-(α,α,α-Trifluoro-m-tolyl)piperazine hydrochloride is soluble in methanol:glacial acetic acid (1:1) at 25 mg/ml.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H336

Hazard Classifications

STOT SE 3

Target Organs

Central nervous system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

T8948-BULK:
T8948-VAR:
T8948-25G:
T8948-5G:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Anne Zwartsen et al.
Neurotoxicology, 66, 87-97 (2018-03-25)
While the prevalence and the use of new psychoactive substances (NPS) is steadily increasing, data on pharmacological, toxicological and clinical effects is limited. Considering the large number of NPS available, there is a clear need for efficient in vitro screening
Ushtana Antia et al.
Journal of forensic sciences, 55(5), 1311-1318 (2010-06-11)
An LC-MS method was developed for benzylpiperazine (BZP) and trifluoromethylphenylpiperazine (TFMPP), constituents of "party pills" or "legal herbal highs," and their metabolites in human blood plasma. Compounds were resolved using a mixture of ammonium formate (pH 4.5, 0.01 M) and

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