T0523

apo-Transferrin from mouse

≥98%

• CAS Number: 11096-37-0
• EC Number: 234-318-8
• MDL number: MFCD00130536
• UNSPSC Code: 12352202
• NACRES: NA.61

Properties

• biological source: mouse
• Quality Level: 200
• Assay: ≥98%
• form: powder
• technique(s): protein quantification: suitable
• solubility: H₂O: 20 mg/mL
• UniProt accession no.: Q921I1
• storage temp.: 2-8°C
• Gene Information: mouse ... Trf(22041)

Description

General description

Transferrin is a 79 kDa protein and possesses two lobes, an N-terminal and a C-terminal lobe, interconnected by a short spacer. The domains interact to form metal ion-binding site.

Application

Apo-Transferrin from mouse has been used in serum protein quantification using surface plasmon resonance (SPR) microarray and serum protein cross-reactivity analysis. It has also been used in the analytical approaches for glycosylation studies like intact glycoprotein analysis, glycopeptide analysis and glycan analysis.

Biochem/physiol Actions

Apo-Transferrin from mouse is a serum protein involved in the transfer of iron to the cells. Apotransferrin can bind two Fe³⁺ ions. In the iron bound state, it is referred to as transferrin. It binds to transferrin receptors in the extracellular surface of cell membrane, internalizes and releases iron in the cytoplasm. Apotransferrin is cycled back to the serum for iron transport.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves