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Safety Information

SRP5252

Sigma-Aldrich

PKC-δ, active, GST tagged human

PRECISIO®, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution

Synonym(s):

MAY1, MGC49908, PRKCD, nPKC-delta

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About This Item

UNSPSC Code:
12352200
NACRES:
NA.32

biological source

human

recombinant

expressed in baculovirus infected Sf9 cells

product line

PRECISIO®

Assay

≥70% (SDS-PAGE)

form

buffered aqueous glycerol solution

specific activity

213-388 nmol/min·mg

mol wt

~104 kDa

NCBI accession no.

NM_006254

application(s)

cell analysis

shipped in

dry ice

storage temp.

−70°C

Gene Information

human ... PRKCD(5580)

Physical form

Supplied in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol.

Preparation Note

After opening, aliquot into smaller quantities and store at -70 °C. Avoid repeating handling and multiple freeze/thaw cycles.

Legal Information

PRECISIO is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

Cartagena Act

Cartagena Act Listed

JAN Code

SRP5252-10UG:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Protein kinase C-d inactivation inhibits the proliferation and survival of cancer stem cells in culture and in vivo.
Chen Z
BMC Cancer (2014)
Cancer Gene List
Ma Hongbao
Cancer Biology & Medicine (2016)
Loss of PKCd Induces Prostate Cancer Resistance to Paclitaxel through Activation of Wnt/?-Catenin Pathway and Mcl-1 Accumulation
M. Luz Flores
Molecular Cancer Therapeutics (2016)
Changes in nuclear protein kinase C-delta holoenzyme, its catalytic fragments, and its activity in polyomavirus-transformed pyF111 rat fibroblasts while proliferating and following exposure to apoptogenic topoisomerase-II inhibitors.
Dal Pra I
Experimental Cell Research (1999)
Identification of proteins interacting with protein kinase C-d in hyperthermia-induced apoptosis and thermotolerance of Tca8113 cells.
Liu J
Molecular Medicine Reports (2015)

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