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Merck
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Key Documents

Safety Information

SRP0704

Sigma-Aldrich

BML-259

recombinant

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About This Item

UNSPSC Code:
12352202
NACRES:
NA.77

Assay

>95% (TLC)

form

lyophilized powder

mol wt

~260.4

shipped in

ambient

storage temp.

−20°C

Biochem/physiol Actions

Potent inhibitor of CDK5/p25 (IC50=64 nM). Inhibits CDK2/cyclin E at slightly higher concentration (IC50=98nM) (1). Protects cells against NAC-amyloid-induced cell death (2). Cell permeable. MW=260.4. Purity ?95% by TLC. Formulated as a lyophilized powder. May be dissolved in DMSO (>25 mg/mL) or DMF (30 mg/mL). Stable desicated as supplied at ambient temperature for up to 2 years, or in solution at -20°C for up to 2 months.

Storage and Stability

Store desiccated as supplied at -20°C for up to 2 years. Store solutions at -20°C for up to 2 months.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

SRP0704-25MG:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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