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Key Documents

Safety Information

SRP0452

Sigma-Aldrich

BRD2 (65-187) His tag human

recombinant, expressed in E. coli, ≥90% (SDS-PAGE)

Synonym(s):

FSH, NAT, RING3, RNF3, bromodomain containing 2

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About This Item

UNSPSC Code:
12352200
NACRES:
NA.32

biological source

human

recombinant

expressed in E. coli

Assay

≥90% (SDS-PAGE)

form

aqueous solution

mol wt

15.5 kDa

packaging

pkg of 100 μg

NCBI accession no.

NM_005104

UniProt accession no.

P25440

shipped in

dry ice

storage temp.

−70°C

Gene Information

human ... BRD2(6046)

General description

Human Bromodomain containing 2, also known as BRD2, RING3 or RNF3 (GenBank Accession No. NM_005104) amino-acids 65 – 187 with N-terminal His-tag, MW = 15.5 kDa, expressed in an E. coli expression system.

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

SRP0452-100UG:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Takashi Umehara et al.
FEBS letters, 584(18), 3901-3908 (2010-08-17)
The BET family proteins recognize acetylated chromatin through their two bromodomains, acting as transcriptional activators or tethering viral genomes to the mitotic chromosomes of their host. The structural mechanism for how the N-terminal bromodomain of human BRD2 (BRD2-BD1) deciphers the
Enyuan Shang et al.
Journal of cellular biochemistry, 112(10), 2784-2793 (2011-05-25)
The human BRD2 gene has been linked and associated with a form of common epilepsy and electroencephalographic abnormalities. Disruption of Brd2 in the mouse revealed that it is essential for embryonic neural development and that viable Brd2(+/-) heterozygotes show both

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