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Key Documents

Safety Information

SRP0442

Sigma-Aldrich

UEV1A active human

recombinant, expressed in E. coli, ≥80% (SDS-PAGE)

Synonym(s):

CIR1, CROC1, UBE2V1, ubiquitin-conjugating enzyme E2 variant 1

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About This Item

UNSPSC Code:
12352202
NACRES:
NA.32

biological source

human

recombinant

expressed in E. coli

Assay

≥80% (SDS-PAGE)

form

aqueous solution

mol wt

20 kDa

packaging

pkg of 100 μg

NCBI accession no.

NM_021988

UniProt accession no.

Q13404

shipped in

dry ice

storage temp.

−70°C

Gene Information

human ... UBE2V1(7335)

General description

UEV1A (ubiquitin-conjugating enzyme E2 variant 1), also known as UBE2V1 or CROC-1 (GenBank Accession No. NM_021988) amino acids 2-170 (end) with N-terminal FLAG-tag, MW=20 kDa, expressed in E. coli.

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

SRP0442-100UG:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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D Duong Hau et al.
Biochemistry, 45(32), 9866-9877 (2006-08-09)
Lys(63)-linked polyubiquitination of TRAF2 or TRAF6 is an essential step within the signal transduction cascade responsible for activation of p38, c-Jun N-terminal kinase, and the transcription factor NF-kappaB. Attachment of ubiquitin (Ub) to a TRAF, and conjugation of Ub molecules
T M Thomson et al.
FEBS letters, 423(1), 49-52 (1998-05-15)
The open reading frame YGL087c in the budding yeast Saccharomyces cerevisiae genome encodes a polypeptide highly similar to the human UEV (ubiquitin-conjugating E2 enzyme variant) proteins, which have been proposed to belong to a family of putative dominant negative ubiquitin
L Ma et al.
Oncogene, 17(10), 1321-1326 (1998-10-15)
Acquisition of the immortal phenotype by tumor cells represents an essential and potentially rate-limiting step in tumorigenesis. To identify changes in gene expression that are associated with the early stages of cell immortalization, we compared genetically matched pairs of pre-immortal
Jing Geng et al.
Nature immunology, 16(11), 1142-1152 (2015-09-29)
Mitochondria need to be juxtaposed to phagosomes for the synergistic production of ample reactive oxygen species (ROS) in phagocytes to kill pathogens. However, how phagosomes transmit signals to recruit mitochondria has remained unclear. Here we found that the kinases Mst1

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