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Safety Information

SML3514

Sigma-Aldrich

Corylin

≥98% (HPLC)

Synonym(s):

3-(2,2-Dimethyl-2H-1-benzopyran-6-yl)-7-hydroxy-4H-1-benzopyran-4-one

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About This Item

Empirical Formula (Hill Notation):
C20H16O4
CAS Number:
53947-92-5
Molecular Weight:
320.34
MDL number:
MFCD20260784
UNSPSC Code:
12352200
NACRES:
NA.77

Quality Level

100

Assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

2-8°C

SMILES string

O=C1C2=CC=C(C=C2OC=C1C3=CC4=C(C=C3)OC(C)(C)C=C4)O

InChI key

PWAACAMQKVIVPZ-UHFFFAOYSA-N

Biochem/physiol Actions

Corylin is a flavonoid isolated from fruit and seed of medical herb Psoralea corylifolia that extend the replicative lifespan in yeast by targeting the Gtr1 protein. Also, Corylin extends lifespan in mice fed a high-fat diet. Corylin exhibits numerous pharmacological effects such as antioxidant properties, anti-inflammatory effects, osteoblastic proliferation-stimulating activity, insulin resistance amelioration.
Extend the replicative lifespan in yeast by targeting the Gtr1 protein

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

SML3514-25MG:
SML3514-BULK:
SML3514-VAR:
SML3514-5MG:

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I-Chen Chen et al.
Pharmaceuticals (Basel, Switzerland), 14(10) (2021-10-24)
Acute lung injury (ALI) is a high mortality disease with acute inflammation. Corylin is a compound isolated from the whole plant of Psoralea corylifolia L. and has been reported to have anti-inflammatory activities. Herein, we investigated the therapeutic potential of

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