Skip to Content
Merck
All Photos(1)

Key Documents

View All Documentation

Safety Information

SML3371

Sigma-Aldrich

MS47134

≥98% (HPLC)

Synonym(s):

((1r,3R,5S,7R)-3,5-dimethyladamantane-1-carbonyl)-D-phenylalanine

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C22H29NO3
Molecular Weight:
355.47
UNSPSC Code:
12352200
NACRES:
NA.21

Quality Level

100

Assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

2-8°C

SMILES string

O=C(N[C@H](CC1=CC=CC=C1)C(O)=O)[C@]2(C[C@]3(C)C4)C[C@@H]4C[C@](C3)(C)C2

Biochem/physiol Actions

MS47134 is a potent and selective agonist probe of the GPCR orphan receptor MRGPRX4.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

SML3371-5MG:
SML3371-VAR:
SML3371-BULK:
SML3371-25MG:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Can Cao et al.
Nature, 600(7887), 170-175 (2021-11-19)
The MRGPRX family of receptors (MRGPRX1-4) is a family of mas-related G-protein-coupled receptors that have evolved relatively recently1. Of these, MRGPRX2 and MRGPRX4 are key physiological and pathological mediators of itch and related mast cell-mediated hypersensitivity reactions2-5. MRGPRX2 couples to

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service