SML3034

Tolterodine L-tartrate

≥98% (HPLC)

• Synonym(s): 2-[(1R)-3-[Bis(1-methylethyl)amino]-1-phenylpropyl]-4-methyl-phenol tartrate, Detrusitol, Kabi-2234, PF-346634, PNU-200583, PNU-200583E, UK-233743, s (R)-2-[3­[bis(1-methylethyl)-amino]1-phenylpropyl]-4-methylphenol [R-(R*,R*)]2,3dihydroxybutanedioate (1:1) (salt)
• Empirical Formula (Hill Notation): C₂₂H₃₁NO·C₄H₆O₆
• CAS Number: 124937-52-6
• Molecular Weight: 475.57
• MDL number: MFCD07771985
• UNSPSC Code: 12352200

Properties

• Quality Level: 100
• Assay: ≥98% (HPLC)
• form: powder
• optical activity: [α]/D 26.0 to 32.0°, c = 1 in methanol
• color: white to beige
• solubility: DMSO: 2 mg/mL, clear
• storage temp.: room temp
• SMILES string: O[C@H]([C@@H](O)C(O)=O)C(O)=O.CC(C)N(CC[C@H](c1ccccc1)c2cc(C)ccc2O)C(C)C
• InChI: 1S/C22H31NO.C4H6O6/c1-16(2)23(17(3)4)14-13-20(19-9-7-6-8-10-19)21-15-18(5)11-12-22(21)24;5-1(3(7)8)2(6)4(9)10/h6-12,15-17,20,24H,13-14H2,1-5H3;1-2,5-6H,(H,7,8)(H,9,10)/t20-;1-,2-/m11/s1
• InChI key: TWHNMSJGYKMTRB-KXYUELECSA-N

Description

Biochem/physiol Actions

Tolterodine L-tartrate may be used as a muscarinic receptor antagonist to test its inhibitory effect on voltage-dependent K+ (Kv) channels. It has also been used to test its effects on multiple ion channels.

Tolterodine L-tartrate is a bladder-specific muscarinic antagonist.

Safety Information

• Pictograms: GHS08,GHS09
• Signal Word: Warning
• Hazard Statements: H361d - H411
• Precautionary Statements: P201 - P202 - P273 - P280 - P308 + P313 - P391
• Hazard Classifications: Aquatic Chronic 2 - Repr. 2
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable