Skip to Content
Merck
All Photos(1)

Key Documents

View All Documentation

Safety Information

SML1263

Sigma-Aldrich

Arylquin 1

≥98% (HPLC)

Synonym(s):

3-(2-Fluorophenyl)-N7,N7-dimethylquinoline-2,7-diamine)

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C17H16FN3
CAS Number:
1630743-73-5
Molecular Weight:
281.33
MDL number:
MFCD28580129
UNSPSC Code:
12352200
PubChem Substance ID:
329825755
NACRES:
NA.77

Quality Level

100

Assay

≥98% (HPLC)

form

powder

color

, white to yellow to light brown

solubility

DMSO: 20 mg/mL, clear

storage temp.

2-8°C

SMILES string

NC1=NC2=CC(N(C)C)=CC=C2C=C1C3=CC=CC=C3F

InChI

1S/C17H16FN3/c1-21(2)12-8-7-11-9-14(17(19)20-16(11)10-12)13-5-3-4-6-15(13)18/h3-10H,1-2H3,(H2,19,20)

InChI key

RHAQINSYYSNKKI-UHFFFAOYSA-N

Biochem/physiol Actions

Arylquin 1 is a potent secretagogue of the tumor suppressor protein prostate apoptosis response-4 (Par-4), selectively inducing apoptosis in a variety of cancer cells. Arylquin 1 acts by binding to vimentin, displacing Par-4 from vimentin for secretion. Arylquin 1 produced a dose-dependent secretion of Par-4 at nanomolar concentrations.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

SML1263-BULK:
SML1263-25MG:
SML1263-5MG:
SML1263-VAR:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service