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Safety Information

SML0640

Sigma-Aldrich

2-Methylserotonin maleate

≥95% (HPLC)

Synonym(s):

2-Me-5-HT maleate, 2-Methyl-5-HT maleate, 2-Methyl-5-hydroxytryptamine maleate

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About This Item

Empirical Formula (Hill Notation):
C11H14N2O · C4H4O4
CAS Number:
78263-91-9
Molecular Weight:
306.31
MDL number:
MFCD00082467
UNSPSC Code:
12352200
PubChem Substance ID:
329825573
NACRES:
NA.77

Quality Level

100

Assay

≥95% (HPLC)

form

powder

storage condition

desiccated

color

white to brown

solubility

H2O: 5 mg/mL, clear

storage temp.

2-8°C

SMILES string

OC1=CC2=C(NC(C)=C2CCN)C=C1.OC(/C=C\C(O)=O)=O

InChI

1S/C11H14N2O.C4H4O4/c1-7-9(4-5-12)10-6-8(14)2-3-11(10)13-7;5-3(6)1-2-4(7)8/h2-3,6,13-14H,4-5,12H2,1H3;1-2H,(H,5,6)(H,7,8)/b;2-1-

InChI key

KFEAUMZKRNJEDU-BTJKTKAUSA-N

Biochem/physiol Actions

2-Methylserotonin is a selective full agonist at the 5-HT3 receptor.
2-Methylserotonin maleate, a serotonin type 3 (5-HT3) agonist is used as a training drug in drug discrimination studies. Use of 2-methylserotonin in evolving rats shows to reflect the ontogeny of the spinal 5-HT3 receptor system.

Features and Benefits

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Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

SML0640-25MG:
SML0640-VAR:
SML0640-BULK:
SML0640-5MG:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Antinociceptive effects of intrathecally administered 2-methylserotonin in developing rats
Giordano J
Dev. Brain Res., 98(1), 142-144 (1997)
5-HT3 agonist 2-methylserotonin as a training drug in drug discrimination studies
Glennon R A et al.
Pharmacology, Biochemistry, and Behavior, 41(2), 361-364 (1992)

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