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Safety Information

SML0475

Sigma-Aldrich

CGP36742

≥97% (NMR)

Synonym(s):

P-(3-Aminopropyl)-P-butyl-phosphinic acid, SGS 742

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About This Item

Empirical Formula (Hill Notation):
C7H18NO2P
CAS Number:
123690-78-8
Molecular Weight:
179.20
MDL number:
MFCD00882735
UNSPSC Code:
12352200
PubChem Substance ID:
329825430
NACRES:
NA.77

Quality Level

100

Assay

≥97% (NMR)

form

powder

storage condition

desiccated

color

white to beige

solubility

H2O: 10 mg/mL (clear solution, warmed)

storage temp.

room temp

SMILES string

CCCCP(O)(=O)CCCN

InChI

1S/C7H18NO2P/c1-2-3-6-11(9,10)7-4-5-8/h2-8H2,1H3,(H,9,10)

InChI key

ONNMDRQRSGKZCN-UHFFFAOYSA-N

Biochem/physiol Actions

CGP36742 was the first orally active GABAB-selective antagonist. The IC50 for blocking GABAergic transmission is 36 μM. Oral administration of CGP36742 in rats blocks baclofen-induced neuronal depression, and reduces learning deficit and passive avoidance in an olfactory bulbectomy depression model.

Features and Benefits

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302,H319

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

SML0475-BULK:
SML0475-IP:
SML0475-5MG:
SML0475-VAR:
SML0475-25MG:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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