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Safety Information

SAE0004

Sigma-Aldrich

Kynurenine 3-Monooxygenase, Pseudomonas fluorescens (strain 17400), Recombinant

Synonym(s):

KMO

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About This Item

Enzyme Commission number:
1.14.13.9 (BRENDA, IUBMB)
UNSPSC Code:
12352204
NACRES:
NA.54

form

solution

Quality Level

200

specific activity

≥3 U/mg

mol wt

50,712 Da

shipped in

dry ice

storage temp.

−70°C

General description

Kynurenine 3-monooxygenase (KMO) is a flavoprotein aromatic hydroxylase (FAH) that catalyzes the hydroxylation of L-kynurenine (L-Kyn) to produce 3-hydroxykynurenine (3-OH-Kyn). This activity is central to tryptophan metabolism and also to the production of nicotinamide adenine dinucleotide (NAD) in higher organisms. KMO contains flavin adenine dinucleotide (FAD) as a non-covalent, but tightly bound, co-factor at a 1:1 ratio of co-factor to protein.

Unit Definition

1 unit will oxidize L-kynurenine at 1 mol/min at pH 7.0, 25°C.

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

PDSCL

Deleterious substance

JAN Code

SAE0004-BULK:
SAE0004-VAR:
SAE0004-1MG:
SAE0004-1MG-PW:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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