SAB5900401

Anti-Monkeypox virus/MPXV H3L Antibody (SAA0282)

• Synonym(s): H3L, Monkeypox virus (MPXV)
• UNSPSC Code: 51111800

Properties

• biological source: mouse
• Quality Level: 100
• recombinant: expressed in CHO cells
• conjugate: unconjugated
• antibody form: affinity purified immunoglobulin
• clone: SAA0282, recombinant monoclonal
• Assay: >95% (SDS-PAGE)
• form: liquid
• mol wt: 150 kDa
• species reactivity: monkeypox virus
• concentration: 1 mg/mL
• technique(s): ELISA: 1:2000-1:4000; neutralization: 0.01-10 μg/mL
• color: colorless
• pH: 7.4
• isotype: IgG2a, kappa
• Protein ID accession no.: NP_536520.1
• UniProt accession no.: Q8V4Z2
• shipped in: wet ice
• storage temp.: -65 to -96°C
• target post-translational modification: unmodified

Description

General description

Anti-Monkeypox virus/MPXV H3L Antibody, clone SAA0282 is produced in mouse. The monoclonal antibodies are IgG immunoglobulins, which consist of two heavy chains and two light chains. Each heavy chain contains four domains, and each light chain contains two domains. The antibody binds to the antigen of the monkeypox virus, which is the H3L protein.




Monkeypox virus (MPXV), like smallpox virus, belongs to the genus Orthopoxvirus. Its morphology is consistent with that of orthopoxvirus, with a brick-shaped or oval shape with rounded corners and a size of 200~400nm. Brick-shaped or oval-shaped, covered by a lipoprotein membrane or envelope, with two protein-containing side bodies in the middle, and a thick membrane core containing a large double-stranded DNA gene body. The genome of Mpox virus is a double-stranded DNA, about 197kb long, and the end of the genome contains an identical but opposite terminal inverted repeat sequence. The virus contains 190 open reading frames, 4 of which are located in terminal inverted repeats. The core proteins of monkeypox virus are A29L, A35R, B6R, M1R, H3L.

Specificity

Monoclonal Anti-Monkeypox virus/MPXV H3L Antibody, clone SAA0282 is highly specific and bind to the H3L protein of the virus. This binding inhibits the virus from entering cells, thus preventing infection. The antibodies also trigger the body’s immune system to produce anti-viral proteins that can clear the virus from the body.

Application

ELISA,neutralization

Packaging

100µg per vial / 1 mg per vial

Storage and Stability

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.Store at +4°C short term (1-2 weeks).Store at -20 °C 12 months. Store at -80°C long term.

Safety Information

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 2
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable