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Key Documents

Safety Information

SAB5701803

Sigma-Aldrich

Anti-Phospho-IRF3-S386 antibody produced in rabbit

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

Quality Level

100

antibody product type

primary antibodies

clone

polyclonal

form

liquid

species reactivity

human

concentration

2.28 mg/mL

technique(s)

western blot: 1:500-1:2000

UniProt accession no.

Q14653

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

phosphorylation (pSer386)

Gene Information

human ... IRF3(3661)

General description

This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Immunogen

A synthetic phosphorylated peptide around S386 of human IRF3.

Physical form

Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

SAB5701803-100UL:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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