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Key Documents

Safety Information

SAB5700823

Sigma-Aldrich

Anti-SERPINE1 antibody produced in rabbit

Synonym(s):

PAI, PAI-1, PAI1, PLANH1, SERPINE1

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

Quality Level

100

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

43
 45

species reactivity

rat, human, mouse

concentration

2.11 mg/ml

technique(s)

immunofluorescence: 1:50-1:200
western blot: 1:500-1:2000

UniProt accession no.

P05121

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... SERPINE1(5054)

General description

This gene encodes a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 24-402 of human SERPINE1 (NP_000593.1).

Physical form

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Storage and Stability

Store at -20℃. Avoid freeze / thaw cycles.

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

SAB5700823-100UL:

Certificates of Analysis (COA)

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