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Key Documents

Safety Information

SAB5700432

Sigma-Aldrich

Anti-Phospho-IκBα-S32/36 antibody produced in rabbit

Synonym(s):

EDAID2, IKB alpha, IKBA, MAD-3, NFKBI, NFKBIA

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.43

biological source

rabbit

Quality Level

100

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

35

species reactivity

human, mouse

concentration

0.54 mg/ml

technique(s)

western blot: 1:500-1:1000

UniProt accession no.

P25963

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

phosphorylation (pSer32/pSer36)

Gene Information

human ... NFKBIA(4792)

General description

This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease.

Immunogen

A synthetic phosphorylated peptide around S32 & S36 of human IκBα (NP_065390.1).

Physical form

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Storage and Stability

Store at -20℃. Avoid freeze / thaw cycles.

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

SAB5700432-100UL:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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