SAB5500174

Anti-S6 Ribosomal Protein (phospho S240/244) antibody, Rabbit monoclonal

recombinant, expressed in proprietary host, clone SP45, affinity isolated antibody

• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: rabbit
• Quality Level: 100
• recombinant: expressed in proprietary host
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: SP45, monoclonal
• species reactivity: human (tested)
• species reactivity (predicted by homology): chicken, mouse, bovine, frog, pig, dog, rat, rabbit
• technique(s): immunohistochemistry: 1:50
• isotype: IgG
• UniProt accession no.: P62753
• shipped in: wet ice
• storage temp.: 2-8°C
• target post-translational modification: phosphorylation (pSer240/pSer244)
• Gene Information: human ... RPS6(6194)

Description

General description

40S ribosomal protein S6 (also known as RPS6) is a ~31 kDa substrate of p70 S6 kinase (p70S6K) and a major component of translational machinery involved in protein synthesis, cell growth, proliferation, and metabolism. RPS6 undergoes phosphorylation on multiple serines in the carboxyl terminal region in the order 236→235→240→244→247, due to the positions of these amino acid residues on the alpha-helix. Hyperphosphorylation of RPS6 stimulates protein synthesis that mediates progression through the cell cycle.

Immunogen

Synthetic peptide derived from the region of human S6 ribosomal that contains phosphorylated serines 240 and 244.

Features and Benefits

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Physical form

0.1 ml rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 2
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable