SAB5500109

Anti-FOXP3 antibody, Rabbit monoclonal

clone SP97, recombinant, expressed in proprietary host, affinity isolated antibody

• Synonym(s): Anti-AIID, Anti-DIETER, Anti-IPEX, Anti-JM2, Anti-PIDX, Anti-XPID
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: rabbit
• Quality Level: 100
• recombinant: expressed in proprietary host
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: SP97, monoclonal
• species reactivity: human (tested)
• species reactivity (predicted by homology): dog, mouse, bovine, pig, rat
• technique(s): immunohistochemistry: 1:100
• isotype: IgG
• UniProt accession no.: Q9BZS1
• shipped in: wet ice
• storage temp.: 2-8°C
• target post-translational modification: unmodified
• Gene Information: human ... FOXP3(50943)

Description

General description

FOXP3 (a 431 amino acid protein) is a member of the forkhead/winged-helix family of transcriptional regulators and is highly conserved across mammals. FOXP3 is essential for normal immune homeostasis. FOXP3 is stably and constitutively expressed at a high level in CD25 + CD4 positive regulatory T cells, at a low level in CD4 positive/CD25 negative cells, and is absent in CD4 negative/CD8 positive T cells. FOXP3 may be a master regulatory gene and a more specific marker of regulatory T cells than other T cells.

Immunogen

Synthetic peptide corresponding to C-terminus of human FOXP3 protein.

Features and Benefits

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Physical form

0.1 ml rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 2
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable