SAB4300064

Anti-phospho-G3BP1 (pSer²³²) antibody produced in rabbit

affinity isolated antibody

• Synonym(s): Anti-G3BP antibody produced in rabbit, Anti-GTPase activating protein (SH3 domain) binding protein 1 antibody produced in rabbit, Anti-HDH-VIII antibody produced in rabbit, Anti-MGC111040 antibody produced in rabbit
• MDL number: MFCD02262927
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: rabbit
• Quality Level: 100
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: ~60 kDa
• species reactivity: human
• concentration: 1 mg/mL
• technique(s): immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100; indirect immunofluorescence: 1:100-1:200; western blot: 1:500-1:1000
• isotype: IgG
• immunogen sequence: (S-S-SP-P-A)
• NCBI accession no.: NP_005745.1
• UniProt accession no.: Q13283
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: phosphorylation (pSer232)
• Gene Information: human ... G3BP1(10146)

Description

Immunogen

Peptide sequence around phosphorylation site of serine 232 (S-S-S(p)-P-A), according to the protein G3BP1.

Features and Benefits

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Target description

May be a regulated effector of stress granule assembly. Phosphorylation-dependent sequence-specific endoribonuclease in vitro. Cleaves exclusively between cytosine and adenine and cleaves MYC mRNA preferentially at the 3'-UTR. ATP- and magnesium-dependent helicase. Unwinds preferentially partial DNA and RNA duplexes having a 17 bp annealed portion and either a hanging 3' tail or hanging tails at both 5'- and 3'-ends. Unwinds DNA/DNA, RNA/DNA, and RNA/RNA substrates with comparable efficiency. Acts unidirectionally by moving in the 5' to 3' direction along the bound single-stranded DNA.

Physical form

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable