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Key Documents

Safety Information

SAB3501286

Sigma-Aldrich

Anti-gp120 antibody produced in rabbit

affinity isolated antibody

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

liquid

species reactivity

human immunodeficiency virus 1

concentration

1 mg/mL

technique(s)

western blot: suitable

isotype

IgG

UniProt accession no.

P04578

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human immunodeficiency virus 1 ... gp120(155971)

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General description

Human immunodeficiency virus type 1 (HIV-1) entry into target cells is directed by the envelope (Env) glycoproteins, which are present on the surface of HIV-1 virion or infected cells in the form of trimers consisting of gp120/gp41 complexes. The surface subunit, gp120, initiates the entry process by interacting sequentially with the CD4 receptor and a co-receptor CCR5 or CXCR4, thereby inducing a conformational change that allows the transmembrane (TM) gp41 subunit to mediate fusion between viral and target cell membranes. Cleavage of Env into its gp120 and gp41 components is necessary for activation of its fusogenic activity.

Immunogen

gp120 antibody was raised against a peptide corresponding to 15 amino acids near the center of HIV-1 gp120.

Application

gp120 antibody can be used for Western blot at 1 - 2 μg/mL.

Physical form

Supplied in PBS containing 0.02% sodium azide.

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Storage Class Code

12 - Non Combustible Liquids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

SAB3501286-100UG:

Certificates of Analysis (COA)

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