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Safety Information

S7401

Sigma-Aldrich

Salicylic acid

suitable for plant cell culture

Synonym(s):

2-Hydroxybenzoic acid

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About This Item

Linear Formula:
2-(HO)C6H4CO2H
CAS Number:
69-72-7
Molecular Weight:
138.12
Beilstein:
774890
EC Number:
200-712-3
MDL number:
MFCD00002439
UNSPSC Code:
12352207
PubChem Substance ID:
24899745
NACRES:
NA.71

grade

for cell biology

vapor density

4.8 (vs air)

vapor pressure

1 mmHg ( 114 °C)

Assay

≥99% (HPLC)

form

powder

technique(s)

cell culture | plant: suitable

bp

211 °C (lit.)

mp

158-161 °C (lit.)

solubility

ethanol: 50 mg/mL

density

1.44 g/cm3 at 20 °C

SMILES string

OC(=O)c1ccccc1O

InChI

1S/C7H6O3/c8-6-4-2-1-3-5(6)7(9)10/h1-4,8H,(H,9,10)

InChI key

YGSDEFSMJLZEOE-UHFFFAOYSA-N

Gene Information

human ... ALB(213) , PTPN1(5770)

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General description

Salicylic acid (SA) is a phenolic compound produced in plants.

Application

Salicylic acid has been used:
  • to study its effects on glandular trichomes in Artemisia annua
  • to study its effects on DNA methylation in Taraxacum alatum andTaraxacum hemicyclum
  • to study its effects on parasite epidemics in Lolium arundinaceum

Biochem/physiol Actions

Salicylic acid (SA) plays a role in endogenous signaling for plant disease resistance. SA is also involved in mediating thermogenesis and symptom development.

Signal Word

Danger

Hazard Statements

H302,H318,H361d

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1 - Repr. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

314.6 °F - closed cup

Flash Point(C)

157 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

ISHL Indicated Name

Substances Subject to be Indicated Names

ISHL Notified Names

Substances Subject to be Notified Names

JAN Code

S7401-BULK:
S7401-VAR:
S7401-500G:
S7401-100G:

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Certificates of Analysis (COA)

Lot/Batch Number
SLCF2890
SLCF2889
SLCF2886
SLBZ5366
SLBW0822

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Salicylic acid

Anders Kjær et al.
AoB PLANTS, 2012, pls018-pls018 (2012-07-27)
Glandular trichomes (GT) of Artemisia annua produce valuable compounds for pharmaceutical and industrial uses, most notably the anti-malarial artemisinin. Our aim was to find out whether the density, number and size of GT can be manipulated to advantage by environmental
E Benfeldt et al.
Acta dermato-venereologica, 79(5), 338-342 (1999-09-24)
Our aim was to simultaneously investigate 2 techniques for in vivo sampling of peripheral compartment pharmacokinetics after systemic administration of acetylsalicylic acid. Ten volunteers were given 2 g acetylsalicylic acid orally. Blood samples and dialysates from 4 microdialysis probes inserted
S Zaugg et al.
Journal of chromatography. B, Biomedical sciences and applications, 752(1), 17-31 (2001-03-20)
Acetylsalicylic acid (Aspirin) is rapidly metabolized to salicylic acid (salicylate) and other compounds, including gentisic acid and salicyluric acid. Monitoring of salicylate and its metabolites is of toxicological, pharmacological and biomedical interest. Three capillary electrophoresis (CE) methods featuring alkaline aqueous
Dorothea Ellinger et al.
Plant physiology, 161(3), 1433-1444 (2013-01-22)
A common response by plants to fungal attack is deposition of callose, a (1,3)-β-glucan polymer, in the form of cell wall thickenings called papillae, at site of wall penetration. While it has been generally believed that the papillae provide a
Yunlong Du et al.
Proceedings of the National Academy of Sciences of the United States of America, 110(19), 7946-7951 (2013-04-25)
Removal of cargos from the cell surface via endocytosis is an efficient mechanism to regulate activities of plasma membrane (PM)-resident proteins, such as receptors or transporters. Salicylic acid (SA) is an important plant hormone that is traditionally associated with pathogen
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