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Safety Information

S5758

Sigma-Aldrich

Sodium tetrathionate dihydrate

≥98% (titration)

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About This Item

Linear Formula:
NaO3SS2SO3Na · 2H2O
CAS Number:
13721-29-4
Molecular Weight:
306.27
MDL number:
MFCD00150868
UNSPSC Code:
12352302
PubChem Substance ID:
24899672
NACRES:
NA.26

Assay

≥98% (titration)

solubility

H2O: 200 + 4mL H2O mg, clear to hazy, colorless to faintly yellow

density

2.1 g/mL at 25 °C (lit.)

storage temp.

2-8°C

SMILES string

O.O.[Na+].[Na+].[O-]S(=O)(=O)SSS([O-])(=O)=O

InChI

1S/2Na.H2O6S4.2H2O/c;;1-9(2,3)7-8-10(4,5)6;;/h;;(H,1,2,3)(H,4,5,6);2*1H2/q2*+1;;;/p-2

InChI key

HAEPBEMBOAIUPN-UHFFFAOYSA-L

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Application


  • Gaussia princeps luciferase: a bioluminescent substrate for oxidative protein folding.: Sodium tetrathionate dihydrate is used to study its impact on the oxidative folding of proteins, utilizing Gaussia princeps luciferase as a bioluminescent substrate. This study advances understanding of protein chemistry and bioluminescence applications in biochemical assays (Yu T et al., 2018).

    • https://doi.org/10.2174/092986612800190973
    https://doi.org/10.1080/10826068.2011.544230
    https://doi.org/10.11150/kansenshogakuzasshi.83.380
  • A spectroscopic investigation into the reaction of sodium tetrathionate with cysteine.: The research utilizes spectroscopic methods to study the reaction between sodium tetrathionate dihydrate and cysteine, providing insights into the chemical interactions and potential applications in biochemistry and molecular biology (Church JS et al., 2008).

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

S5758-25G:
S5758-BULK:
S5758-100G:
S5758-VAR:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Poul Bennekou et al.
Blood cells, molecules & diseases, 48(2), 102-109 (2011-12-06)
The vanadate-induced increase in passive uptake of calcium and cobalt and their interference were studied in human red cells using (45)Ca and (57)Co as tracers. Vanadate is a potent inhibitor of the Ca-pump in red cells, although in fed cells
Rich Boden et al.
Environmental microbiology, 12(10), 2688-2699 (2010-05-21)
A new pathway of dimethylsulfide (DMS) metabolism was identified in a novel species of Gammaproteobacteria, Methylophaga thiooxidans sp. nov., in which tetrathionate (S(4)O(6)(2-)) was the end-product of DMS oxidation. Inhibitor evidence indicated that DMS degradation was initiated by demethylation, catalysed
Parameth Thiennimitr et al.
Proceedings of the National Academy of Sciences of the United States of America, 108(42), 17480-17485 (2011-10-05)
Conventional wisdom holds that microbes support their growth in vertebrate hosts by exploiting a large variety of nutrients. We show here that use of a specific nutrient (ethanolamine) confers a marked growth advantage on Salmonella enterica serovar Typhimurium (S. Typhimurium)
Bomba Dam et al.
Research in microbiology, 158(4), 330-338 (2007-05-19)
Chemolithotrophic oxidation of reduced sulfur compounds was studied in the betaproteobacterium Tetrathiobacter kashmirensis in correlation with its transposon (Tn5-mob)-inserted mutants impaired in sulfur oxidation (Sox(-)) and found to be carried out via the tetrathionate intermediate (S(4)I) pathway. The group of
Mei Kikumoto et al.
Applied and environmental microbiology, 79(1), 113-120 (2012-10-16)
Thiosulfate dehydrogenase is known to play a significant role in thiosulfate oxidation in the acidophilic, obligately chemolithoautotroph, Acidithiobacillus ferrooxidans. Enzyme activity measured using ferricyanide as the electron acceptor was detected in cell extracts of A. ferrooxidans ATCC 23270 grown on
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