Skip to Content
Merck
All Photos(1)

Key Documents

View All Documentation

Safety Information

S5571

Sigma-Aldrich

β-Synuclein histidine-tagged human

N-terminal, recombinant, expressed in E. coli, ≥90% (SDS-PAGE), lyophilized powder

Synonym(s):

SNCB

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

MDL number:
MFCD08705537
UNSPSC Code:
12352202
NACRES:
NA.32

recombinant

expressed in E. coli

Quality Level

200

Assay

≥90% (SDS-PAGE)

form

lyophilized powder

UniProt accession no.

Q16143

shipped in

dry ice

storage temp.

−20°C

Gene Information

human ... SNCB(6620)

Biochem/physiol Actions

β-synuclein is an acidic, neuronal protein considered to be a non-amyloidogenic homolog of α-synuclein. It has been postulated that β-synuclein could act as a physiological inhibitor of α-synuclein aggregation and thus protect the central nervous system from the neurotoxic effects of α-synuclein.

Reconstitution

Reconstitute with 0.5 mL water (~1 mg/mL). Store in working aliquots at −20 °C.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

S5571-VAR:
S5571-500UG:
S5571-500UG-PW:
S5571-BULK:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Makoto Hashimoto et al.
The Journal of biological chemistry, 279(22), 23622-23629 (2004-03-18)
Recent studies have shown that the neurodegenerative process in disorders with Lewy body formation, such as Parkinson's disease and dementia with Lewy bodies, is associated with alpha-synuclein accumulation and that beta-synuclein might protect the central nervous system from the neurotoxic

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service