RAB0386

Brain Natriuretic Peptide EIA Kit

for serum, plasma, culture supernatant and cell lysates

• Synonym(s): Gamma-brain natriuretic peptide, Natriuretic peptides B , BNP
• UNSPSC Code: 12352200
• NACRES: NA.32

Properties

• species reactivity: human, mouse, rat
• packaging: kit of 96 wells (12 strips x 8 wells)
• technique(s): ELISA: suitable; enzyme immunoassay: suitable
• input: sample type serum; sample type culture supernatant(s); sample type plasma; sample type cell lysate
• assay range: inter-assay cv: <15%; intra-assay cv: <10%; sensitivity: 1.66 pg/mL; standard curve range: 0.1–1000 pg/mL
• detection method: colorimetric
• shipped in: wet ice
• storage temp.: −20°C
• Gene Information: human ... NPPB(4879)

Description

General description

The BNP Enzyme Immunoassay (EIA) Kit is an in vitro quantitative assay for detecting BNP peptide based on the principle of Competitive Enzyme Immunoassay.

Immunogen

Brain Natriuretic Peptide, synthetic peptide

Application

For research use only. Not for use in diagnostic procedures.
Brain natriuretic peptide EIA Kit has been used to measure brain natriuretic peptide (BNP) secreted in human neonatal ventricular cardiomyocyte culture.

Biochem/physiol Actions

Brain natriuretic peptide (BNP) expressed in mammalian brain and atrial natriuretic peptide (ANP) facilitates various physiological functions including regulation of blood pressure and cardiac remodeling. BNP acts as a potential biomarker of high left ventricular end-diastolic pressure in patients with symptomatic left ventricular (LV) dysfunction. Elevated expression of BNP is observed in acute myocardial infarction (AMI) patients. BNP is also implicated in several biological functions such as diuresis, natriureis, hypotensive action and inhibition of aldosterone secretion.

Kit Components Also Available Separately

• RABHRP3 HRP-Streptavidin

Safety Information

• Pictograms: GHS05
• Signal Word: Warning
• Hazard Statements: H290
• Precautionary Statements: P234 - P390
• Hazard Classifications: Met. Corr. 1
• Storage Class Code: 8A - Combustible, corrosive hazardous materials
• WGK: WGK 3