R882A-05N

Rat Astrocytes: RA, neonatal

• UNSPSC Code: 41106514
• NACRES: NA.81

Properties

• biological source: rat brain (Rat brain)
• Quality Level: 100
• packaging: pkg of 500,000 cells
• manufacturer/tradename: Cell Applications, Inc
• growth mode: Adherent
• morphology: glial
• technique(s): cell culture | mammalian: suitable
• relevant disease(s): seizures
• shipped in: dry ice
• storage temp.: −196°C

Description

General description

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Rat astrocytes (RA) are derived from rat cerebral cortex. Astrocytes are the most abundant cells in the central nervous system where they perform many functions, such as providing mechanical support and nutrients to neurons and removal of wastes from neurons; providing signaling to endothelial cells; regulating neurogenesis and controlling synaptic function. As the recognition of the importance of astrocytes in nervous system is increasing, RA serve as a useful in vitro model for exploring the diversity of astrocytes functions.Characterization: Stained positive for GFAP.Rat Astrocytes (RA) and Rat Brain Microvascular Endothelial Cells (RBMEC), both from Cell Applications, Inc., have been used to assess neuroprotective capabilities of bioenergy stabilizers in an in vitro model of stroke (Liu, 2013) and to investigates the effects of astrocytes on brain microvascular endothelial cells in relation to iron transport pathway (McCarthy, 2014).

Cell Line Origin

Brain

Application

Neuroscience research, mechanical & biochemical support, ion balance, nutrient provision, waste removal, cell signaling, regulation of neurogenesis, control of synaptic function, astrocyte function, gene expressino, injury repair, gliotransmitter release, neuronal excitability.

Components

Basal Medium containing 10% FBS & 10% DMSO

Quality

Each lot was tested for proper morphology, Population Doublings, Negative for HIV, Hepatitis B, Hepatitis C, mycoplasma, bacteria, and fungi.

Preparation Note

• 2nd passage, >500,000 cells in Basal Medium containing 10% FBS & 10% DMSO
• Can be cultured at least 10 doublings

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable