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Safety Information

P9827

Sigma-Aldrich

Polycytidylic acid–Agarose

lyophilized powder

Synonym(s):

Poly(C)–Agarose potassium salt

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About This Item

MDL number:
MFCD00165464
UNSPSC Code:
41106500
NACRES:
NA.56

form

lyophilized powder

Quality Level

200

extent of labeling

0.25-1.0 mg per mL

matrix

cross-linked 4% beaded agarose

matrix activation

cyanogen bromide

matrix attachment

amino

matrix spacer

1 atom

swelling

1 g swells to ~5 mL

storage temp.

−20°C

Application

Polycytidylic acid-agarose is used in protein chromatography, affinity chromatography and specialy resins. Polycytidylic acid has been used to study the preferential induction of apoptosis in the rainbow trout macrophage cell line. Polycytidylic acid has also been used to develop two analytical methods for human secretory-type ribonuclease.

Physical form

Lyophilized powder stabilized with lactose

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

P9827-250MG:
P9827-1G:
P9827-VAR:
P9827-BULK:

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Certificates of Analysis (COA)

Lot/Batch Number
SLCJ9938
SLBW2467
SLBR5739V
SLBQ6034V
SLBN8605V

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C-P Benny Yiu et al.
Biochemical and biophysical research communications, 343(1), 311-318 (2006-03-18)
Dribble (DBE) is an essential protein in Drosophila that belongs to the evolutionarily conserved Krr1p protein family. Proteins in this family are localised in the cell nucleolus and are important for the processing of ribosomal RNAs. However, little is known
Preparation of sepharose-bound poly (rI:rC).
A F Wagner et al.
Biochemical and biophysical research communications, 45(1), 184-189 (1971-10-01)
S J Dewitte-Orr et al.
Fish & shellfish immunology, 18(4), 279-295 (2004-11-25)
The rainbow trout macrophage cell line RTS11 was found to be considerably more sensitive than rainbow trout fibroblast (RTG-2) and Chinook salmon epithelial (CHSE-214) cell lines to killing by macromolecular synthesis inhibitors, actinomycin D (AMD) and cycloheximide (CHX), a synthetic
D Nadano et al.
Analytical biochemistry, 212(1), 111-116 (1993-07-01)
Two analytical methods for human secretory-type ribonuclease, which are based on polycytidylic acid/ethidium bromide fluorescence, have been developed. The first is a method for measurement of secretory-type ribonuclease activity utilizing the radial diffusion of ribonuclease in a thin agarose gel
W R Paulding et al.
The Journal of biological chemistry, 274(4), 2532-2538 (1999-01-16)
The stability of mRNA for tyrosine hydroxylase (TH), the rate-limiting enzyme in catecholamine synthesis, is regulated by oxygen tension in the pheochromocytoma-derived PC12 cell line. We previously identified a pyrimidine-rich 27-base-long protein-binding sequence in the 3'-untranslated region of TH mRNA
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