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Safety Information

P1925

Millipore

Protein A–Agarose macrobeads

aqueous suspension

Synonym(s):

Protein A resin

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About This Item

MDL number:
MFCD00165563
UNSPSC Code:
41106500
NACRES:
NA.56

form

aqueous suspension

Quality Level

200

extent of labeling

~6 mg per mL

matrix activation

cyanogen bromide

matrix spacer

1 atom

capacity

~6 mg/mL binding capacity (human IgG)

storage temp.

2-8°C

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General description

Protein A is an immunoglobulin (Ig)-binding protein that might be suitable for low-pressure antibody isolation. It is used to purify large amounts of IgG and binds to the Fc part of the antibody at the CH2–CH3 interface. Protein A-agarose is used for affinity chromatography, antibody purification and characterization, and protein A, G and L resins.

Application

Protein A–Agarose macrobeads has been used in immunoprecipitation. It has been used to study the effects of protein A immunoadsorption in patients with chronic dilated cardiomyopathy as well as to study multiple sclerosis and gastric cancer.

Physical form

Suspension in 0.9% NaCl containing 15Mm Sodium Azide

Hazard Statements

H412

Precautionary Statements

P273 - P501

Hazard Classifications

Aquatic Chronic 3

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

PDSCL

Poisonous substance

JAN Code

P1925-10ML:4548173205489
P1925-5ML:4548173205502
P1925-5ML-PW:
P1925-BULK:
P1925-VAR:
P1925-1ML-PW:
P1925-1ML:4548173205496

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Certificates of Analysis (COA)

Lot/Batch Number
098M4088V
11171027
097M4143V
105M4064V
11140111

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C Cullin et al.
Yeast (Chichester, England), 10(1), 105-112 (1994-01-01)
In this paper are described a set of new high-copy-number yeast vectors, which are specially designed for the conditional expression of epitope-tagged proteins in vivo. One of the major advantages of these plasmids is that they allow polymerase chain reaction-amplified
B Blumbach et al.
Journal of cell science, 111 ( Pt 17), 2635-2644 (1998-08-14)
Porifera (sponges) are the oldest extant metazoan phylum. Dissociated sponge cells serve as a classic system to study processes of cell reaggregation. The reaggregation of dissociated cells is mediated by an extracellularly localized aggregation factor (AF), based on heterophilic interactions
C Wagner-Hülsmann et al.
Glycobiology, 6(8), 785-793 (1996-12-01)
The cDNA for the full-length lectin from the marine sponge Geodia cydonium was cloned. Analysis of the deduced aa sequence revealed that this lectin belongs to the group of galectins. The full-length galectin, which was obtained also in a recombinant
Nanmei Liu et al.
The Journal of nutritional biochemistry, 18(9), 597-608 (2007-03-17)
Transcuprein is a high-affinity copper carrier in the plasma that is involved in the initial distribution of copper entering the blood from the digestive tract. To identify and obtain cDNA for this protein, it was purified from rat plasma by
Chung Fai Wong et al.
Oncogene, 24(21), 3525-3534 (2005-03-01)
Recently, E2F function has expanded to include the regulation of differentiation in human epidermal keratinocytes (HEKs). We extend these findings to report that in HEKs, Sp1 is a differentiation-specific activator and a downstream target of E2F-mediated suppression of the differentiation-specific
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