MSKT0001

SILu^™MAb K1 Pharmacokinetic Kit

• Synonym(s): PK Kit
• UNSPSC Code: 41105331
• NACRES: NA.41

Properties

• suitability: suitable for mass spectrometry
• storage temp.: 2-8°C

Description

General description

All critical reagents necessary to perform the assay are provided in the kit. The plate-based format avoids the high cost and potential LC column blockage associated with bead-based enrichment formats. Sample preparation with the SILu^™MAb PK kit can be performed in under 5 hours and consists of coating wells with high-specificity capture antibody, followed by immunoaffinity enrichment and rapid, in-plate trypsin digestion. The resulting digest is ready for injection, with no SPE or other cleanup required.

Application

The SILu^™MAb K1 Pharmacokinetic (PK) kit enables a robust, high-throughput assay for quantification of human IgG1 antibody in animal sera by LC-MS/MS.

Storage and Stability

Store the kit at 2-8°C. The kit is stable for two years refrigerated.

Legal Information

SILu is a trademark of Sigma-Aldrich Co. LLC

Safety Information

• Pictograms: GHS02,GHS06,GHS08
• Signal Word: Danger
• Hazard Statements: H226,H301 + H311 + H331,H370
• Precautionary Statements: P210 - P233 - P280 - P301 + P310 - P303 + P361 + P353 - P304 + P340 + P311
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 3 - STOT SE 1
• Target Organs: Eyes,Central nervous system
• Storage Class Code: 3 - Flammable liquids
• Flash Point(F): 75.2 °F
• Flash Point(C): 24 °C