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Safety Information

M9375

Sigma-Aldrich

D-Methionine

≥98% (HPLC)

Synonym(s):

(R)-2-Amino-4-(methylmercapto)butyric acid, D-2-Amino-4-(methylthio)butanoic acid

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About This Item

Empirical Formula (Hill Notation):
C5H11NO2S
CAS Number:
348-67-4
Molecular Weight:
149.21
Beilstein:
1722293
EC Number:
206-483-6
MDL number:
MFCD00002622
UNSPSC Code:
12352209
PubChem Substance ID:
24897327
NACRES:
NA.26

Quality Level

200

Assay

≥98% (HPLC)

form

powder

color

white

mp

273 °C

application(s)

cell analysis
peptide synthesis

SMILES string

CSCC[C@@H](N)C(O)=O

InChI

1S/C5H11NO2S/c1-9-3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)/t4-/m1/s1

InChI key

FFEARJCKVFRZRR-SCSAIBSYSA-N

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Biochem/physiol Actions

D-methionine has been shown to rescue noise-induced hearing loss.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

M9375-5G:
M9375-25G:
M9375-100G:
M9375-BULK:
M9375-100MG:
M9375-VAR:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Kathleen Campbell et al.
Hearing research, 282(1-2), 138-144 (2011-09-20)
We have previously reported rescue from noise-induced auditory brainstem response (ABR) threshold shifts with d-methionine (d-met) administration 1 h after noise exposure. The present study investigated further d-met rescue intervals at 3, 5 and 7 h post-noise exposure. Chinchillas laniger were exposed
Audrey S Vanhove et al.
Applied and environmental microbiology, 86(11) (2020-03-30)
While only a subset of Vibrio cholerae strains are human diarrheal pathogens, all are aquatic organisms. In this environment, they often persist in close association with arthropods. In the intestinal lumen of the model arthropod Drosophila melanogaster, methionine and methionine
Calvin Wu et al.
Journal of neural transmission (Vienna, Austria : 1996), 121(7), 683-693 (2014-02-18)
Antioxidants are well known for their neuroprotective properties against reactive oxygen species in cortical neurons and auditory cells. We recently identified L-carnitine and D-methionine to be among agents that provide such protection. Here, we investigated their neuronal modulatory actions. We
Tobias Dörr et al.
PLoS genetics, 10(6), e1004433-e1004433 (2014-06-20)
The bacterial cell wall, which is comprised of a mesh of polysaccharide strands crosslinked via peptide bridges (peptidoglycan, PG), is critical for maintenance of cell shape and survival. PG assembly is mediated by a variety of Penicillin Binding Proteins (PBP)
Guo-Lin Chen et al.
Gene, 435(1-2), 53-62 (2009-04-07)
Tryptophan hydroxylase-2 (TPH2) catalyzes the synthesis of neuronal serotonin, a major neurotransmitter involved in many brain functions and psychiatric disorders. We have previously revealed a critical role of the human TPH2 (hTPH2) 5'-UTR in gene expression regulation. This study aimed
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