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M6385

Sigma-Aldrich

Methyl cellulose

viscosity: 25 cP

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About This Item

CAS Number:
9004-67-5
MDL number:
MFCD00081763
UNSPSC Code:
12352201
PubChem Substance ID:
24897005
NACRES:
NA.25

Quality Level

200

form

powder

color

white to off-white

viscosity

20-30 cP, 2 % in water(20 °C)

SMILES string

[*]OC[C@H]1O[C@@H](O[C@@H]2[C@@H](CO[*])O[C@@H](O[*])[C@H](O[*])[C@H]2O[*])[C@H](O[*])[C@@H](O[*])[C@@H]1O[*]

InChI key

YLGXILFCIXHCMC-JHGZEJCSSA-N

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General description

Methyl cellulose (MC) is a simple derivative of cellulose.

Application

Methyl cellulose has been used:
  • as a supplement for culturing multicellular spheroids of SH-SY5Y cells
  • as a supplement for culturing tumor cell spheroids
  • to generate and study the rheological behavior of aqueous mullite-albumin-methylcellulose systems

Biochem/physiol Actions

Methyl cellulose (MC) acts as a laxative and is hydrophilic. It has therapeutic effects against constipation, irritable bowel syndrome, and diverticulosis due to its bulk-forming and stool softening properties. MC has the potential to treat patients with ileostomies and colostomies. It may also be used as a stabilizer and emulsifier. MC is a component of eye drops and contact lens solutions.

Other Notes

To gain a comprehensive understanding of our extensive range of Polysaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

M6385-250G:
M6385-100G:
M6385-1KG:
M6385-500G:
M6385-BULK:
M6385-VAR:

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Certificates of Analysis (COA)

Lot/Batch Number
SLCL8091
SLCK0989
SLCJ3756
SLCD5155
SLCC2541

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Rheological behavior of aqueous mullite-albumin-methylcellulose systems
Sandoval M, et al.
Ceramics International, 43(9) (2017)
Dirk van den Brand et al.
Biochimica et biophysica acta, 1860(6), 1342-1349 (2018-03-20)
Drug delivery into tumors and metastases is a major challenge in the eradication of cancers such as epithelial ovarian carcinoma. Cationic cell-penetrating peptides (CPPs) are a promising group of delivery vehicles to mediate cellular entry of molecules that otherwise poorly
Methylcellulose
Kieth H.
xPharm: The Comprehensive Pharmacology Reference, 1-3 (2007)
Jesse E Hanson et al.
Cell reports, 30(2), 381-396 (2020-01-16)
NMDA receptors (NMDARs) play subunit-specific roles in synaptic function and are implicated in neuropsychiatric and neurodegenerative disorders. However, the in vivo consequences and therapeutic potential of pharmacologically enhancing NMDAR function via allosteric modulation are largely unknown. We examine the in vivo effects
Maria Chiara Lionetti et al.
Journal of clinical medicine, 9(8) (2020-08-14)
Melanoma is one of the most aggressive and highly resistant tumors. Cell plasticity in melanoma is one of the main culprits behind its metastatic capabilities. The detailed molecular mechanisms controlling melanoma plasticity are still not completely understood. Here we combine
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