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Safety Information

M1520

Sigma-Aldrich

IgM, Kappa from murine myeloma

clone TEPC 183, ascites fluid, lyophilized powder

Synonym(s):

Mouse IgM-κ

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About This Item

MDL number:
MFCD00283897
UNSPSC Code:
12352203
NACRES:
NA.46

biological source

mouse

Quality Level

200

conjugate

unconjugated

antibody form

ascites fluid

clone

TEPC 183, monoclonal

form

lyophilized powder

storage temp.

2-8°C

target post-translational modification

unmodified

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General description

The TEPC-183 tumor line that produces mouse IgM is a tetramethylpentadecane (pristane) induced plasmacytoma, originated and carried intraperitoneally in BALB/c mice. Mouse consists of five immunoglobulin classes- IgM, IgG, IgA, IgD and IgE. IgM is present on the surface of B lymphocytes in its monomeric form.

Application

IgM, Kappa from murine myeloma has been used as a control to study its effects on brain derived synaptic plasticity.

Biochem/physiol Actions

IgM antibodies are present as pentamers in serum and are produced in response to antigens.

Reconstitution

Reconstitute with 1 ml deionized water.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

M1520-BULK:
M1520-VAR:
M1520-5MG-PW:
M1520-5MG:
IXO67923:

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Certificates of Analysis (COA)

Lot/Batch Number
069M4882V
027M4808V
061M4799V
048K4873
060K9179

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The Immunoglobulins: Structure and Function (1998)
D M Reinitz et al.
Infection and immunity, 58(7), 2337-2342 (1990-07-01)
The T-cell dependency of B-cell responses to variant surface glycoprotein (VSG) epitopes exposed in their native surface conformation on Trypanosoma brucei rhodesiense clone LouTat 1 was investigated. T-cell requirements were examined by analyses of gamma globulin preparations derived from trypanosome-infected
Molecular Genetics of Immunoglobulin, 17 (1987)
A monoclonal antibody against synthetic A beta dimer assemblies neutralizes brain-derived synaptic plasticity-disrupting A beta
ONuallain B, et al.
Journal of Neurochemistry, 119(1), 189-201 (2011)
M Lohoff et al.
Infection and immunity, 56(8), 2120-2124 (1988-08-01)
The well-established polyclonal B-cell stimulation in the lymphoid organs in mice infected with Leishmania major is thought to be dependent on T cells. Here we present clear experimental evidence that this is indeed the case by showing that BALB/c-derived, L3T4-positive
View All Related Papers

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