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Safety Information

M045080

Sigma-Aldrich

6-Tetrachloro-Fluorescein Phosphoramidite

configured for PerkinElmer, configured for Polygen

Synonym(s):

6-(4, 7, 2′, 7′-Tetrachloro-3′,6′-dipivaloylfluoresceinyl-6-carboxamido)-hexyl-1-O-(2-cyanoethyl)-(N,N-diisopropyl)-phosphoramidite

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About This Item

Empirical Formula (Hill Notation):
C46H54N3O10Cl4P
Molecular Weight:
981.72
MDL number:
MFCD01940926
UNSPSC Code:
41116105
PubChem Substance ID:
329817791
NACRES:
NA.21

Assay

≥97% (31P-NMR)
≥97.0% (reversed phase HPLC)

color

white to off-white, powder

suitability

conforms to structure for H-NMR
conforms to structure for H-NMR

compatibility

configured for PerkinElmer
configured for Polygen

storage temp.

−70°C

SMILES string

O=C(C1=C(Cl)C=C(C(NCCCCCCOP(N(C(C)C)C(C)C)OCCC#N)=O)C(Cl)=C12)OC32C4=C(C=C(OC(C(C)(C)C)=O)C(Cl)=C4)OC5=CC(OC(C(C)(C)C)=O)=C(Cl)C=C53

InChI

1S/C46H54Cl4N3O10P/c1-25(2)53(26(3)4)64(59-19-15-16-51)58-18-14-12-11-13-17-52-40(54)27-20-32(49)37-38(39(27)50)46(63-41(37)55)28-21-30(47)35(61-42(56)44(5,6)7)23-33(28)60-34-24-36(31(48)22-29(34)46)62-43(57)45(8,9)10/h20-26H,11-15,17-19H2,1-10H3,(H,52,54)

InChI key

RKVIHIDUTMZQEZ-UHFFFAOYSA-N

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Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

PDSCL

Deleterious substance

JAN Code

M045080-0.1MMOL:

Certificates of Analysis (COA)

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Jun Yu et al.
PloS one, 4(7), e6445-e6445 (2009-08-04)
Stringently controlled conditional expressing systems are crucial for the functional characterization of genes. Currently, screening of multiple clones to identify the tightly controlled ones is necessary but time-consuming. Here, we describe a system fusing Tet (tetracycline)-inducible elements, BAC (bacterial artificial
W Gao et al.
Cell death and differentiation, 18(10), 1598-1607 (2011-04-09)
In yeast, activation of ATG1/ATG13 kinase complex initiates autophagy. This mechanism of autophagy initiation is conserved, as unc-51-like kinase 1 (ULK1) and unc-51-like kinase 2 (ULK2) are two mammalian functional homologues of ATG1 and form similar complex with mammalian ATG13.

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