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M0284

Sigma-Aldrich

Anti-Mouse IgG (Fc specific) F(ab′)2 fragment antibody produced in goat

2.0 mg/mL, affinity isolated antibody, buffered aqueous solution

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About This Item

MDL number:
MFCD00162625
UNSPSC Code:
12352203
NACRES:
NA.46

biological source

goat

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

secondary antibodies

clone

polyclonal

form

buffered aqueous solution

concentration

2.0 mg/mL

technique(s)

indirect ELISA: suitable

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

General description

Immunoglobulin G (IgG) belongs to the immunoglobulin family and is a widely expressed serum antibody. An immunoglobulin has two heavy chains and two light chains connected by a disulfide bond.It mainly helps in immune defense. It is a glycoprotein.IgG is a major class of immunoglobulin.Mouse consists of five immunoglobulin classes- IgM, IgG, IgA, IgD and IgE. Mouse IgG is further divided into five classes- IgG1, IgG2a, IgG2b and IgG3.
Immunoglobulin G (IgG) is a glycoprotein antibody that regulates immune responses such as phagocytosis and is also involved in the development of autoimmune diseases . Mouse IgGs have four distinct isotypes, namely, IgG1, IgG2a, IgG2b, and IgG3. IgG1 regulates complement fixation in mice .

Immunogen

Purified mouse IgG

Application

Anti-Mouse IgG (Fc specific) F(ab′)2 fragment antibody produced in goat has been used in CD117/Sca-1 fluorescence-activated cell sorting (FACS) analysis and to detect bound factor H in factor H binding assay.

Biochem/physiol Actions

Immunoglobulin G (IgG) participates in hypersensitivity type II and type III reactions. IgG helps in opsonization, complement fixation and antibody dependent cell mediated cytotoxicity.

Other Notes

Antibody adsorbed with bovine, equine and human serum proteins

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 0.05% sodium azide.

Preparation Note

Adsorbed to reduce background with bovine, equine, or human samples.
Useful when trying to avoid background staining due to the presence of Fc receptors.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

12 - Non Combustible Liquids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

M0284-VAR:
M0284-.25ML:
M0284-.5ML:
M0284-BULK:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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The Laboratory Rat (1998)
Liliana Grajales et al.
Journal of molecular and cellular cardiology, 48(4), 735-745 (2010-01-12)
Bone marrow-derived mesenchymal stem cells (BM-MSCs) can be induced to differentiate into myogenic cells. Despite their potential, previous studies have not been successful in producing a high percentage of cardiac-like cells with a muscle phenotype. We hypothesized that cardiac lineage
Producing an Anti-β2 Integrin MAb By a Hybridoma Cell Line in a 2-Liter Stirred-Tank Bioreactor.
Kallel, H, and Fathallah, D, M.
Bioprocess International, 1, 54-59 (2003)
The Immunoglobulins: Structure and Function (1998)
Delayed enrichment of mesenchymal cells promotes cardiac lineage and calcium transient development
Grajales L, et al.
Journal of Molecular and Cellular Cardiology, 48(4), 735-745 (2010)
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