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Key Documents

Safety Information

L0780

Sigma-Aldrich

Latex beads, amine-modified polystyrene, fluorescent blue

aqueous suspension, 0.05 μm mean particle size

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About This Item

MDL number:
MFCD00131492
UNSPSC Code:
12352116
NACRES:
NA.56

form

aqueous suspension

Quality Level

100

composition

Solids, 2.5%

technique(s)

cell based assay: suitable

mean particle size

0.05 μm

fluorescence

λex ~360 nm; λem ~420 nm

application(s)

cell analysis

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Application

Latex beads, amine-modified polystyrene, fluorescent blue has been used:
  • to study its effects on the concentration-response relationship of bacterial cell viability
  • in the preparation of nanoparticles
  • as a model nanoparticle to study interactions with human blood and platelets

Biochem/physiol Actions

Polystyrene latex beads can be used to create latex agglutination systems. Polystyrene latex beads have been used to study the transmission of Mycobacterium leprae, the causative pathogen of leprosy, as well as to develop a method for mass screening for both pulmonary and extrapulmonary tuberculosis.

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

L0780-VAR:
L0780-1ML:
L0780-BULK:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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J-M Gineste et al.
Journal of microscopy, 243(2), 172-178 (2011-03-08)
The forward scattering of light in a conventional inverted optical microscope by nanoparticles ranging in diameter from 10 to 50nm has been used to automatically and quantitatively identify and track their location in three-dimensions with a temporal resolution of 200ms.
Optical signatures of small nanoparticles in a conventional microscope.
Eann A Patterson et al.
Small (Weinheim an der Bergstrasse, Germany), 4(10), 1703-1706 (2008-09-10)
INDUCTION OF EPIGENETIC RESPONSE TO AMINO-MODIFIED POLYSTYRENE NANOPARTICLES IN HUMAN CELLS
Koprinarova M, et al.
Comparative clinical pathology, 71(10) (2018)
Catherine McGuinnes et al.
Toxicological sciences : an official journal of the Society of Toxicology, 119(2), 359-368 (2010-12-03)
There is evidence that nanoparticles (NP) can enter the bloodstream following deposition in the lungs, where they may interact with platelets. Polystyrene latex nanoparticles (PLNP) of the same size but with different surface charge-unmodified (umPLNP), aminated (aPLNP), and carboxylated (cPLNP)-were
J Geys et al.
Toxicology letters, 160(3), 218-226 (2005-09-03)
Recent studies indicate that inhaled ultrafine particles can pass into the circulation. To study this translocation in an in vitro model three types of pulmonary epithelial cells were examined. The integrity of the cell monolayer was verified by measuring the
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