K1136
Ketorolac tris salt
≥99%, crystalline
Synonym(s):
(±)-5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid tris salt, Toradol
About This Item
Recommended Products
biological source
synthetic (organic)
Quality Level
Assay
≥99%
form
crystalline
solubility
H2O: soluble 15 mg/mL, clear, colorless to faintly yellow (stable at least one month at −20 °C.)
storage temp.
room temp
SMILES string
NC(CO)(CO)CO.OC(=O)C1CCn2c1ccc2C(=O)c3ccccc3
InChI
1S/C15H13NO3.C4H11NO3/c17-14(10-4-2-1-3-5-10)13-7-6-12-11(15(18)19)8-9-16(12)13;5-4(1-6,2-7)3-8/h1-7,11H,8-9H2,(H,18,19);6-8H,1-3,5H2
InChI key
BWHLPLXXIDYSNW-UHFFFAOYSA-N
Gene Information
human ... PTGS1(5742) , PTGS2(5743)
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Application
- as an intraperitoneal injection in mice to study the effect of ketorolac on expression of c-Fos (a human proto-oncogene) in ARC (arcuate nucleus of the hypothalamus) POMC (proopiomelanocortin) -EGFP (enhanced green fluorescent protein) neurons
- to treat mice in order to show that this treatment does not prevent IL-1β-mediated inhibition of Agouti-related protein (AgRP) secretion from murine hypothalamic explants
- as an analgesic medication to treat rats induced with acute inflammatory joint injury by injecting carrageenan into the ankle
Biochem/physiol Actions
Caution
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Target Organs
Respiratory system
Storage Class Code
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
Regulatory Listings
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JAN Code
K1136-VAR:
K1136-1G:
K1136-5G:
K1136-BULK:
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Chromatograms
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