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Safety Information

I8265

Sigma-Aldrich

IgG from sheep serum

technical grade, ≥80% (SDS-PAGE), buffered aqueous solution

Synonym(s):

Sheep IgG

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About This Item

MDL number:
MFCD00165834
UNSPSC Code:
12352203
NACRES:
NA.46

conjugate

unconjugated

grade

technical grade

Assay

≥80% (SDS-PAGE)

form

buffered aqueous solution

shipped in

dry ice

storage temp.

−20°C

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General description

IgG antibody subtype is the most abundant serum immunoglobulins of the immune system. It is secreted by B cells and is found in blood and extracellular fluids and provides protection from infections caused by bacteria, fungi and viruses. Maternal IgG is transferred to fetus through the placenta that is vital for immune defence of the neonate against infections
Purified Sheep IgG is isolated from pooled normal sheep serum by fractionation.

Application

Technical grade sheep IgG may be used as an economical alternative to the reagent grade immunoglobulins, in applications where high purity is not required. Sheep IgG was used as negative control in 293T cells (human embryonic kidney cells) and Madin-Darby canine kidney (MDCK) cells at a working antibody dilution of 1:40.

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.2, containing 15 mM sodium azide

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

I8265-10MG:
I8265-5X100MG:
I8265-50MG:
I8265-100MG:
I8265-BULK:
I8265-VAR:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Thomas Zürcher et al.
The Journal of antimicrobial chemotherapy, 58(4), 723-732 (2006-08-08)
Viruses resistant to zanamivir have been generated in vitro, but no resistant virus has yet been isolated from a zanamivir-treated immunocompetent patient. In contrast most resistant viruses isolated from oseltamivir-treated patients correspond to those selected in vitro. However, despite mutations
J B Richards et al.
Theriogenology, 52(6), 1055-1066 (2000-03-29)
Sixteen ram lambs (5 m.o. old, 45 +/- 1.5 kg) received a control diet (50% concentrate, no locoweed, n = 4), locoweed (20% locoweed for 21 d, n = 4), MUSE (2 mL i.m. of MUSE containing 5 mg selenium
S Hashira et al.
Pediatrics international : official journal of the Japan Pediatric Society, 42(4), 337-342 (2000-09-15)
Maternal immunoglobulin G (IgG), transferred across the placenta to the fetus during intrauterine life, is an important component of the neonatal immunological defence mechanisms against infection. There is controversy with respect to differences in placental transfer of the different IgG

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