Skip to Content
Merck
All Photos(4)

Documents

Safety Information

I4375

Sigma-Aldrich

Inosine 5′-diphosphate sodium salt

≥96%

Synonym(s):

IDP

Sign Into View Organizational & Contract Pricing
All Photos(4)

About This Item

Empirical Formula (Hill Notation):
C10H14N4O11P2
CAS Number:
81012-88-6
Molecular Weight:
428.19
MDL number:
MFCD00043058
UNSPSC Code:
41106305
PubChem Substance ID:
24896053
NACRES:
NA.51

biological source

microbial

Assay

≥96%

form

powder

solubility

water: 50 mg/mL, clear to very slightly hazy, colorless

storage temp.

−20°C

SMILES string

[Na+].[Na+].[Na+].O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP([O-])(=O)OP([O-])([O-])=O)n2cnc3C(=O)NC=Nc23

InChI

1S/C10H14N4O11P2.3Na/c15-6-4(1-23-27(21,22)25-26(18,19)20)24-10(7(6)16)14-3-13-5-8(14)11-2-12-9(5)17;;;/h2-4,6-7,10,15-16H,1H2,(H,21,22)(H,11,12,17)(H2,18,19,20);;;/q;3*+1/p-3/t4-,6-,7-,10-;;;/m1.../s1

InChI key

CPIQGMJSIPVOOS-MSQVLRTGSA-K

Application

Inosine 5′-diphosphate sodium salt has been used for hystoenzymatic demonstration of nucleoside diphosphatase (NDPase).

Preparation Note

Prepared from muscle or bacterial ADP.

Pictograms

Health hazard
GHS08

Signal Word

Warning

Hazard Statements

H371

Hazard Classifications

STOT SE 2

Target Organs

Eyes,Central nervous system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

ISHL Indicated Name

Substances Subject to be Indicated Names

ISHL Notified Names

Substances Subject to be Notified Names

JAN Code

I4375-25MG:4548174008621
I4375-VAR:
I4375-1G:
I4375-BULK:
I4375-500MG:4548174008638
I4375-100MG:4548174008614
I4375-10MG:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Customers Also Viewed

Slide 1 of 2

1 of 2

Coenzyme A hydrate ≥85% (UV, HPLC)

Sigma-Aldrich

C4282

Coenzyme A hydrate

Hypoxanthine ≥99.0%

Sigma-Aldrich

H9377

Hypoxanthine

Edwin K Jackson et al.
The Journal of pharmacology and experimental therapeutics, 321(2), 799-809 (2007-02-23)
Stimulation of adenylyl cyclase causes cellular efflux of cAMP, and cAMP (unlike adenosine) is stable in blood. Therefore, it is conceivable that cAMP could function as a circulating adenosine prohormone by local target-organ conversion of distally released cAMP to adenosine
Increased number of microglia in the brain of severe combined immunodeficient (SCID) mice
Lorke DE, et al.
Histochemistry and Cell Biology, 130(4), 693-697 (2008)
Satoko Ohkubo et al.
European journal of pharmacology, 577(1-3), 35-43 (2007-09-20)
In C6 glioma cells, adenine nucleotides, especially AMP, and adenosine inhibited cell proliferation in time- and concentration-dependent manners. alpha,beta-methylene-ADP, an ecto-5'-nucleotidase inhibitor, suppressed the hydrolysis of AMP and reversed the inhibition of cell growth induced by AMP but not by
John A Duley et al.
Therapeutic drug monitoring, 27(5), 647-654 (2005-09-22)
Metabolism of thiopurine drugs--azathioprine, 6-mercaptopurine, and 6-thioguanine--has provided a powerful pharmacogenetic model incorporating polymorphism of the enzyme thiopurine methyltransferase (TPMT) and the primary active metabolite, thioguanine nucleotide (TGN). However, a sense of uncertainty about the usefulness of TGNs and other
CD4 microglial expression correlates with spontaneous clinical improvement in the acute Lewis rat EAE model
Almolda B, et al.
Journal of Neuroimmunology, 209(1-2), 65-80 (2009)
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service