Skip to Content
Merck
All Photos(2)

Key Documents

More Documents

Safety Information

I3639

Sigma-Aldrich

Isoetharine mesylate salt

Synonym(s):

4-[1-Hydroxy-2-[(1-methylethyl)amino]butyl]-1,2-benzenediol mesylate salt

Sign Into View Organizational & Contract Pricing
All Photos(2)

About This Item

Empirical Formula (Hill Notation):
C13H21NO3 · CH4O3S
CAS Number:
7279-75-6
Molecular Weight:
335.42
EC Number:
230-695-8
MDL number:
MFCD00133422
UNSPSC Code:
12352200
PubChem Substance ID:
24278491
NACRES:
NA.77

originator

Sanofi Aventis

Quality Level

200

storage temp.

2-8°C

SMILES string

CS(O)(=O)=O.CCC(NC(C)C)C(O)c1ccc(O)c(O)c1

InChI

1S/C13H21NO3.CH4O3S/c1-4-10(14-8(2)3)13(17)9-5-6-11(15)12(16)7-9;1-5(2,3)4/h5-8,10,13-17H,4H2,1-3H3;1H3,(H,2,3,4)

InChI key

SOYAGMVKMXZVNZ-UHFFFAOYSA-N

Gene Information

human ... ADRB1(153) , ADRB2(154) , ADRB3(155)

Application

Isoetharine mesylate salt has been used:
  • as an adrenergic drug to test its effect on embryo implantation in 4-day pregnant mice
  • as a substrate for recombinant human sulfotransferase (SULT) in SULT assay to monitor conjugation reaction
  • as a β-2 agonist in collision-induced dissociation (CID) mass spectrometry analysis

Biochem/physiol Actions

Isoetharine is an agonist for β-adrenergic receptors and is a bronchodilator. It is a catecholic drug metabolized by sulfotransferases and is present in human urine and plasma as a sulfated metabolite. Catechol O-methyltransferase (COMT) also mediates the methylation of isoetharine in the metabolic conjugation pathway.

Features and Benefits

This compound was developed by Sanofi Aventis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302 + H312 + H332

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

I3639-1G:
I3639-VAR:
I3639-BULK:
I3639-10G:
I3639-5G:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service