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G8876

Sigma-Aldrich

Glycogen from rabbit liver

≥85% dry basis (enzymatic)

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About This Item

CAS Number:
EC Number:
MDL number:
UNSPSC Code:
12352201
NACRES:
NA.25

biological source

rabbit liver

Assay

≥85% dry basis (enzymatic)

form

powder

color

white to off-white

solubility

water: 40 mg/mL, clear to turbid, colorless to light yellow

storage temp.

2-8°C

InChI

1S/C24H42O21/c25-1-5-9(28)11(30)16(35)22(41-5)39-4-8-20(45-23-17(36)12(31)10(29)6(2-26)42-23)14(33)18(37)24(43-8)44-19-7(3-27)40-21(38)15(34)13(19)32/h5-38H,1-4H2/t5-,6-,7-,8-,9-,10-,11+,12+,13-,14-,15-,16-,17-,18-,19-,20-,21+,22+,23-,24-/m1/s1

InChI key

BYSGBSNPRWKUQH-UJDJLXLFSA-N

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General description

Glycogen is a branched polymer of glucose synthesized by animal cells for energy storage and release. It is constructed of predominantly α1→4 glycosidic bonds with branches created through α1→6 glycosidic bonds.

Application

  • Glycogen from rabbit liver has been use as a standard for measurement of the hepatic glycogen content.
  • In the1,4-α-D gIucan:orthophosphate α-glucosyl transferase assay, it has been used in the assay mixture.
  • It has also been used as a standard for myocardial tissue glycogen analysis.

Biochem/physiol Actions

Glycogen from rabbit liver helps in maintaining blood glucose levels by regulating the release of glucose in between meals. It also provides energy during sudden, strenuous activity. Two important areas of glycogen storage are the liver and skeletal muscle.

Preparation Note

Prepared by a modification of the procedure of Bell, et al., Biochem. J., 28, 882 (1934).

Other Notes

To gain a comprehensive understanding of our extensive range of Polysaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

G8876-10G:
G8876-5G:
G8876-1G:
G8876-BULK:
G8876-500MG:
G8876-VAR:


Certificates of Analysis (COA)

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Janne R Hingst et al.
Molecular metabolism, 16, 24-34 (2018-08-11)
A single bout of exercise followed by intake of carbohydrates leads to glycogen supercompensation in prior exercised muscle. Our objective was to illuminate molecular mechanisms underlying this phenomenon in skeletal muscle of man. We studied the temporal regulation of glycogen
Relationship between beta-adrenergic receptor numbers and physiological responses during experimental canine myocardial ischemia.
Mukherjee A, et al.
Circulation Research, 50, 735-741 (1982)
Developmental changes in ovine myocardial glucose transporters and insulin signaling following hyperthermia-induced intrauterine fetal growth restriction.
Barry JS, et al.
Experimental Biology and Medicine (Maywood, N.J.), 231, 566-575 (2006)
Glycogen Metabolism
Berg JM, et al.
Biochemistry (2002)
Daily rhythms in metabolic liver enzymes and plasma glucose require a balance in the autonomic output to the liver.
Cailotto C, et al.
Endocrinology, 149, 1914-1925 (2008)

Articles

Glucose metabolism is regulated by the opposing actions of insulin and glucagon. Insulin is released from pancreatic ß cells in response to high blood glucose levels and regulates glucose metabolism through its actions on muscle, liver, and adipose tissue.

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