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Safety Information

G8507

Sigma-Aldrich

α-Galactosidase from green coffee beans

ammonium sulfate suspension, ≥9 units/mg protein

Synonym(s):

alpha-Galactosidase, α-D-Galactoside galactohydrolase, Melibiase

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About This Item

CAS Number:
9025-35-8
Enzyme Commission number:
3.2.1.22 (BRENDA, IUBMB)
MDL number:
MFCD00130486
UNSPSC Code:
12352204
NACRES:
NA.54

form

ammonium sulfate suspension

Quality Level

200

specific activity

≥9 units/mg protein

storage temp.

2-8°C

Related Categories

General description

α-Galactosidase from green coffee beans is encoded by the GLA gene.

Application

α-Galactosidase from green coffee beans has been used to assess the specificity of anti- α-Galactosidase antibodies. It has also been used in inhibition assay to assess N-guanidino derivatives of 1,5-dideoxy-1,5-imino-d-xylitol activity.

Biochem/physiol Actions

α-Galactosidase from green coffee beans cleaves the terminal α-galactose from the oligosaccharides. α-Galactosidase deficiency is associated with Fabry disease.

Unit Definition

One unit will hydrolyze 1.0 μmole of p-nitrophenyl α-D-galactoside to p-nitrophenol and D-galactose per min at pH 6.5 at 25 °C.

Physical form

Suspension in 3.2 M (NH4)2SO4 solution, pH 6.0, containing BSA

inhibitor

Product No.
Description
Pricing

substrate

Product No.
Description
Pricing

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

G8507-50UN:
G8507-BULK:
G8507-25UN:
G8507-1UN:
G8507-5UN:
G8507-VAR:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Pig xenogeneic antigen modification with green coffee bean alpha-galactosidase
Luo Y, et al.
Xenotransplantation, 6(4), 238-248 (1999)
A prophylactic alpha-Gal-based glycovaccine effectively protects against murine acute Chagas disease
Portillo S, etal.
NPJ vaccines, 4(1), 13-13 (2019)
Structure-function relationships in alpha-galactosidase A
Garman SC
Acta Paediatrica (Oslo, Norway : 1992), 96, 6-16 (2007)
Amblyomma sculptum tick saliva: alpha-Gal identification, antibody response and possible association with red meat allergy in Brazil
Araujo RN, et al.
International Journal For Parasitology, 46(3), 213-220 (2016)
Orthoester functionalized N-guanidino derivatives of 1, 5-dideoxy-1, 5-imino-d-xylitol as pH-responsive inhibitors of beta-glucocerebrosidase
Sevvsek A, et al.
MedChemComm, 8(11), 2050-2054 (2017)
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Instructions for working with enzymes supplied as ammonium sulfate suspensions

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