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F9384

Sigma-Aldrich

Anti-Mouse IgA (α-chain specific)−FITC antibody produced in goat

affinity isolated antibody, buffered aqueous solution

Synonym(s):

Goat Anti-Mouse IgA (α-chain specific)−Fluorescein isothiocyanate

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About This Item

MDL number:
MFCD00162617
UNSPSC Code:
12352203
NACRES:
NA.46

biological source

goat

conjugate

FITC conjugate

antibody form

affinity isolated antibody

antibody product type

secondary antibodies

clone

polyclonal

form

buffered aqueous solution

technique(s)

direct immunofluorescence: 1:16

storage temp.

2-8°C

target post-translational modification

unmodified

General description

IgA antibody is secretory antibody and is present abundantly in mucous linings of gastrointestinal, respiratory and genitourinary tracts, tears and saliva. Thus secretory IgA contributes to the humoral defense mechanism against the pathogens on mucosal surfaces
Anti-Mouse IgA (α-chain specific)−FITC antibody is specific for α chain of mouse IgA. The purified IgA fraction is conjugated to Fluorescein Isothiocyanate (FITC), Isomer I.

Immunogen

Purified mouse IgA

Application

Anti-Mouse IgA (α-chain specific)−FITC antibody may be used for direct immunofluorescent labeling of mouse spleen cells at a minimum working dilution of 1:16. The antibody was used to label platelets from human or mice after incubation with primary antibody against β3 integrin.

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin and 15 mM sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

F9384PROC:
F9384-1ML:
F9384-.5ML:
F9384-2ML:
F9384-BULK:
F9384-VAR:

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Heidi Tiller et al.
Transfusion, 52(7), 1446-1457 (2012-01-19)
Fetal and neonatal alloimmune thrombocytopenia (FNAIT) is a severe bleeding disorder caused by maternal antibody-mediated destruction of fetal or neonatal platelets (PLTs). Results from our recent large screening study suggest that the pathophysiology of FNAIT is more similar to hemolytic
B Manoury-Schwartz et al.
European journal of immunology, 25(12), 3235-3242 (1995-12-01)
Native type II collagen (CII) is a high molecular-weight fibrillar molecule which induces a chronic polyarthritis in mice expressing the H-2q haplotype. The present study was initiated to analyze the processing and the presentation of this nonglobular protein by H-2q
Hao-Jing Wen et al.
Molecular medicine reports, 19(1), 660-666 (2018-11-16)
A high level of oxidized low‑density lipoproteins (oxLDLs) is an independent risk factor for cardiovascular disease. The aim of the present study was to investigate whether insulin‑like growth factor‑1 (IGF‑1) protected endothelial progenitor cells (EPCs) from injury caused by ox‑LDLs
Robert W Garvey et al.
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Mounting evidence suggests that the serotonin system serves in signal transmission to regulate insulin secretion in pancreatic islets of Langerhans. Among the 5-HT receptor subtype found in pancreatic islets, serotonin receptor 1A (5-HT1A ) demonstrates a unique ability to inhibit
D C Shieh et al.
Autoimmunity, 15(2), 123-135 (1993-01-01)
Type I, insulin-dependent diabetes (IDD) results from an autoimmune response against the insulin producing pancreatic beta cells. This autoimmune reaction involves both humoral and cell-mediated factors; nevertheless, the relative role of each remains unresolved. Furthermore, while adoptive transfer experiments have
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